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المؤلفHabib, S.
المؤلفZavahir, S.
المؤلفAbusrafa, A.E.
المؤلفAbdulkareem, A.
المؤلفSobolciak, P.
المؤلفLehocky, M.
المؤلفVesela, D.
المؤلفHumpolicek, P.
المؤلفPopelka, A.
تاريخ الإتاحة2023-10-09T07:34:21Z
تاريخ النشر2021
اسم المنشورPolymers
المصدرScopus
معرّف المصادر الموحدhttp://dx.doi.org/10.3390/polym13020206
معرّف المصادر الموحدhttp://hdl.handle.net/10576/48351
الملخصMany polymer materials have found a wide variety of applications in biomedical indus-tries due to their excellent mechanical properties. However, the infections associated with the bio-film formation represent serious problems resulting from the initial bacterial attachment on the polymeric surface. The development of novel slippery liquid-infused porous surfaces (SLIPSs) repre-sents promising method for the biofilm formation prevention. These surfaces are characterized by specific microstructural roughness able to hold lubricants inside. The lubricants create a slippery layer for the repellence of various liquids, such as water and blood. In this study, effective antimi-crobial modifications of polyethylene (PE) and polyurethane (PU), as commonly used medical pol-ymers, were investigated. For this purpose, low-temperature plasma treatment was used initially for activation of the polymeric surface, thereby enhancing surface and adhesion properties. Subse-quently, preparation of porous microstructures was achieved by electrospinning technique using polydimethylsiloxane (PDMS) in combination with polyamide (PA). Finally, natural black seed oil (BSO) infiltrated the produced fiber mats acting as a lubricating layer. The optimized fiber mats' production was achieved using PDMS/PA mixture at ratio 1:1:20 (g/g/mL) using isopropyl alcohol as solvent. The surface properties of produced slippery surfaces were analyzed by various microscopic and optics techniques to obtain information about wettability, sliding behavior and surface morphology/topography. The modified PE and PU substrates demonstrated slippery behavior of an impinged water droplet at a small tilting angle. Moreover, the antimicrobial effects of the produced SLIPs using black seed oil were proven against Gram-positive Staphylococcus aureus (S. au-reus) and Gram-negative Escherichia coli (E. coli). 2021 by the authors. Licensee MDPI, Basel, Switzerland.
راعي المشروعThis publication was made possible by Award JSREP07-022-3-010 from the Qatar National Research Fund (a member of The Qatar Foundation). This publication was supported by the Qatar University Collaborative grant number QUCG-CAM-20/21-3. P.H., M.L. and D.V. acknowledge that this work was supported by the Ministry of Education, Youth and Sports of the Czech Republic DKRVO (RP/CPS/2020/001).
اللغةen
الناشرMDPI AG
الموضوعAntimicrobial activity
Electrospinning
Oil infusion
Plasma treatment
Slippery surface
العنوانSlippery liquid-infused porous polymeric surfaces based on natural oil with antimicrobial effect
النوعArticle
الصفحات18-Jan
رقم العدد2
رقم المجلد13
dc.accessType Open Access


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