Show simple item record

AuthorAboelbaha, Shimaa
AuthorZolezzi, Monica
AuthorAbdallah, Oraib
AuthorEltorki, Yassin
Available date2023-11-05T06:14:31Z
Publication Date2023
Publication NamePharmacogenomics and Personalized Medicine
ResourceScopus
ISSN11787066
URIhttp://dx.doi.org/10.2147/PGPM.S410240
URIhttp://hdl.handle.net/10576/49023
AbstractObjective: A wide variety of commercial pharmacogenetic (PGx) tools are available worldwide to guide treatment selection for depression based on individuals’ genetic profiles. However, the use of genetic testing to inform psychiatric care has faced challenges due to the limited training and education for mental health clinicians. The aim of this study was to explore the knowledge, level of engagement, and perspectives on the use of PGx testing when making depression management decisions among practicing psychiatrists within the Middle East and North Africa (MENA) region. Methods: This is a qualitative study using semi-structured interviews. Consenting psychiatrists were interviewed through an online platform (SkypeTM or Microsoft TeamsTM). Interviews were audio recorded, transcribed, and thematically analyzed with the assistance of NVivo® software. Results: Eighteen interviews from 12 countries have been conducted. Analysis of the current interviews produced five major themes including: (1) Overall perceptions and attitudes; (2) Knowledge and awareness; (3) Education, training, and professional experience; (4) Facilitators and barriers; and (5) Ethical dilemmas. These themes support the notion that there is limited, mostly basic, education, knowledge, and training regarding genetic testing in the management of depression, although there is significant interest and willingness in the part of prescribers to adopt this strategy in their practice. Conclusion: The findings of the study suggest that psychiatrists practicing in the MENA region appear to be interested in implementing PGx testing when managing people with depression. However, it is also important to recognize that this cannot be achieved unless more supporting strategies are implemented within their current health system environment.
SponsorOpen Access funding provided by the Qatar National Library.
Languageen
PublisherDove Medical Press Ltd
Subjectdepression
MENA region
mental health
pharmacogenetic testing
psychiatry
qualitative study
TitleMental Health Prescribers' Perceptions on the Use of Pharmacogenetic Testing in the Management of Depression in the Middle East and North Africa Region
TypeArticle
Pagination503-518
Volume Number16
dc.accessType Open Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record