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AuthorJamialahamdi, Tannaz
AuthorMirhadi, Elaheh
AuthorAtkin, Stephen L.
Authorle Roux, Carel W.
AuthorKroh, Matthew
AuthorAlmahmeed, Wael
AuthorEid, Ali H.
AuthorSahebkar, Amirhossein
Available date2023-11-15T07:11:20Z
Publication Date2023-11-01
Publication NameObesity Surgery
Identifierhttp://dx.doi.org/10.1007/s11695-023-06830-w
CitationJamialahamdi, T., Mirhadi, E., Atkin, S. L., le Roux, C. W., Kroh, M., Almahmeed, W., ... & Sahebkar, A. (2023). Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis. Obesity Surgery, 1-9.‏
ISSN09608923
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85173057861&origin=inward
URIhttp://hdl.handle.net/10576/49317
AbstractBackground: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. Methods: Studies included all types of bariatric surgery where SAA was measured before and after the surgical procedure. Results: Meta-analysis of 11 clinical studies (n = 394 individuals) confirmed a significant reduction in SAA following bariatric surgery (SMD: − 0.971, 95% CI: − 2.721, 0.779, p < 0.001). Meta-regression did not show any association between the changes in BMI and the absolute difference in SAA levels. No relationship between the changes in SAA and the length of follow-up was found. Conclusion: Bariatric surgery significantly improved SAA. The decrease in SAA was not related to time after surgery or changes in BMI. Bariatric surgery may thus have an independent effect on SAA. Graphical Abstract: [Figure not available: see fulltext.].
Languageen
Publisherspringer link
SubjectBariatric surgery
Body mass index
Meta-analysis
Meta-regression
Serum amyloid A
TitleEffect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
TypeArticle
Pagination1-9
Issue Number11
Volume Number33
dc.accessType Abstract Only


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