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المؤلفAl-Shami, Khayry
المؤلفAwadi, Sajeda
المؤلفKhamees, Almu'atasim
المؤلفAlsheikh, Ahmad Malek
المؤلفAl-Sharif, Sumaiya
المؤلفAla’ Bereshy, Raneem
المؤلفAl-Eitan, Sharaf F.
المؤلفBanikhaled, Sajedah H.
المؤلفAl-Qudimat, Ahmad R.
المؤلفAl-Zoubi, Raed M.
المؤلفAl Zoubi, Mazhar Salim
تاريخ الإتاحة2023-11-15T08:04:18Z
تاريخ النشر2023-09-01
اسم المنشورHeliyon
المعرّفhttp://dx.doi.org/10.1016/j.heliyon.2023.e20224
الاقتباسAl-Shami, K., Awadi, S., Alsheikh, A. M., Al-Sharif, S., Ala’Bereshy, R., Al-Eitan, S. F., ... & Al Zoubi, M. S. (2023). Estrogens and the risk of breast cancer: A narrative review of literature. Heliyon.‏
الرقم المعياري الدولي للكتاب24058440
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85171832026&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/49335
الملخصIn female mammals, the development and regulation of the reproductive system and non-reproductive system are significantly influenced by estrogens (oestrogens). In addition, lipid metabolism is another physiological role of estrogens. Estrogens act through different types of receptors to introduce signals to the target cell by affecting many estrogen response elements. Breast cancer is considered mostly a hormone-dependent disease. Approximately 70% of breast cancers express progesterone receptors and/or estrogen receptors, and they are a good marker for cancer prognosis. This review will discuss estrogen metabolism and the interaction of estrogen metabolites with breast cancer. The carcinogenic role of estrogen is discussed in light of both conventional and atypical cancers susceptible to hormones, such as prostate, endometrial, and lung cancer, as we examine how estrogen contributes to the formation and activation of breast cancer. In addition, this review will discuss other factors that can be associated with estrogen-driven breast cancer.
اللغةen
الناشرElsevier Ltd
الموضوعBreast cancer
ER
Estrogen
Oestrogen
Risk
العنوانEstrogens and the risk of breast cancer: A narrative review of literature
النوعArticle
رقم العدد9
رقم المجلد9
dc.accessType Open Access


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