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AuthorZlatan, Zvizdic
AuthorCatic, Adna
AuthorZivojevic, Selma
AuthorJonuzi, Asmir
AuthorGlamoclija, Una
AuthorVranic, Semir
Available date2024-01-31T07:18:16Z
Publication Date2023-10-28
Publication NameJournal of Pediatric Urology
Identifierhttp://dx.doi.org/10.1016/j.jpurol.2023.10.027
CitationZvizdic, Z., Catic, A., Zivojevic, S., Jonuzi, A., Glamoclija, U., & Vranic, S. (2023). The correlation between ureteric orifice morphology and primary vesicoureteral reflux grade and the impact on the effectiveness of endoscopic reflux correction. Journal of Pediatric Urology.
ISSN1477-5131
URIhttps://www.sciencedirect.com/science/article/pii/S1477513123004564
URIhttp://hdl.handle.net/10576/51433
AbstractIntroductionEarly diagnosis and treatment of primary vesicoureteral reflux (VUR) are essential for preserving renal function. ObjectivesThe study explored whether preoperative cystoscopic grading of refluxing ureteric orifices (UO) correlated with their shape in an institution with non-performance of hydrodistention of the UO in the diagnosis and grading of VUR. We also assessed the relationship between the UO shape and VUR grade with the effectiveness of endoscopic correction of primary VUR in children. MethodsThis retrospective study included consecutive patients ≤15 years treated for primary VUR. The reflux grade was based on the results of preoperative voiding cystourethrography as mild, moderate, or severe. ResultsFifty-one patients with 77 renal refluxing units (RRU) underwent endoscopic treatment with Deflux®. VUR was bilateral in 51 % of patients. VUR was mild in 13 %, moderate in 53 %, and severe in 34 % of cases. The patients with mild and moderate VUR had stadium-shaped UOs in 60 % and 54 % RRUs, respectively. Horseshoe-shaped UOs constituted 42 % of UOs in patients with severe VUR, followed by 31 % of golf-hole UOs. The reflux resolution rate after the first endoscopic injection was 84 %. The preoperative VUR grade correlated with UOs shape (p < 0.001). No significant correlation between UOs configuration and the outcome of endoscopic treatment was seen (p = 0.452). The preoperative VUR grade negatively correlated with a favorable endoscopic treatment (p = 0.043). Discussion and conclusionOur data indicate ureteral orifice shapes are closely related to preoperative VUR grade. There was no correlation between the UO configuration and the success rate of endoscopic treatment of VUR, in contrast to the significant negative correlation between the VUR grade and the success rate of endoscopic treatment.
Languageen
PublisherElsevier
SubjectPrimary vesicoureteral reflux
Ureteral orifice shape
Endoscopic treatment
Outcome
TitleThe correlation between ureteric orifice morphology and primary vesicoureteral reflux grade and the impact on the effectiveness of endoscopic reflux correction
TypeArticle
ESSN1873-4898
dc.accessType Full Text


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