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AuthorAl-Qahtani, Ahmed A.
AuthorAlabasi, Enas S.
AuthorAbuOdeh, Raed
AuthorThalib, Lukman
AuthorNasrallah, Gheyath K.
Available date2017-01-15T05:30:13Z
Publication Date2016-12-28
Publication NameVirology Journal
Identifierhttp://dx.doi.org/10.1186/s12985-016-0664-6
CitationAl-Qahtani AA, Alabsi ES, AbuOdeh R, Thalib L, Nasrallah GK. Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar. Virology Journal. 2016; 13:208.
URIhttp://hdl.handle.net/10576/5167
AbstractBackground Anelloviruses (TTV, TTMV, and TTMDV) have been associated with non A-G hepatitis. The goal of the current study was to estimate the prevalence of these anelloviruses in Qatar. Methods A total of 607 blood samples (500 healthy donors, and 53 HBV-and 54 HCV-positive patients) representing different nationalities were tested for the presence of TTV, TTMV, and TTMDV DNA by nested PCR. Results Prevalence rates for the three viruses were high in all studied groups, and exceeding 95% in the HBV group (for TTV and TTMDV). Infection with more than one type of viruses was common and significant in most of the positive patients (p < 0.05) and ranging from 55.4% for TTV/TTMV and TTMV/TTMDV co-infections in the healthy group, to 96.3% for TTV/TTMV co-infections in the HBV group. Further, and as with most previous studies, no significant association was found between anelloviruses infections and age, nationality, or gender (p > 0.05) albeit the detection of higher infection rates among females and Qatari subjects. Conclusion This was the first published study to look at prevalence of Anellowviruses in the Middle East. High prevalence rates of the three viruses in all studied groups was noted. Further studies are needed to explore and compare the different genotypes of these viruses in the region.
SponsorThis work was made possible by UREP grant # (UREP 15-015-3-006) from the Qatar National Research Fund (a member of Qatar Foundation).
Languageen
PublisherBioMed Central
SubjectAnelloviruses
HBV
HCV
PCR
TitlePrevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar
TypeArticle
Issue Number208
Volume Number13
ESSN1743-422X
dc.accessType Open Access


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