An Arabic Version of the cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-Cog): Reliability, validity, and normative data
Author | Jemaa, Sonia Ben |
Author | Romdhane, Neila Attia |
Author | Bahri-Mrabet, Amel |
Author | Jendli, Adel |
Author | Gall, Didier Le |
Author | Bellaj, Tarek |
Available date | 2024-02-12T10:12:13Z |
Publication Date | 2017-01-01 |
Publication Name | Journal of Alzheimer's Disease |
Identifier | http://dx.doi.org/10.3233/JAD-170222 |
Citation | Ben Jemaa, S., Attia Romdhane, N., Bahri-Mrabet, A., Jendli, A., Le Gall, D., & Bellaj, T. (2017). An Arabic version of the cognitive subscale of the Alzheimer’s Disease Assessment Scale (ADAS-cog): reliability, validity, and normative data. Journal of Alzheimer's Disease, 60(1), 11-21. |
ISSN | 13872877 |
Abstract | The Alzheimer's Disease Assessment Scale's cognitive subscale (ADAS-Cog) is the most widely used instrument for screening cognitive dysfunction in Alzheimer's disease. The aim of the present study was to develop an Arabic version of this scale (A-ADAS-Cog), examine its psychometric properties (reliability and validity), and provide normative data. The A-ADAS-Cog), an Arabic version of the Mini-Mental State Examination (A-MMSE), and a Standardized Clinical Dementia Rating Scale (CDR) were administered to three Tunisian groups: 124 normal controls (NC), 33 patients with non-Alzheimer dementia (N-AD), and 25 patients with Alzheimer's disease (AD). The A-ADAS-Cog scores were significantly affected by age and education. A correction table was constructed to control these effects. The results showed that the A-ADAS-Cog has good internal consistency and reliability (α=0.82 for AD). The test-retest reliability of the A-ADAS-Cog was stable over time (r=0.97). An evaluation of the construct validity of the A-ADAS-Cog using principal component analysis led to a solution with three factors (memory, language and praxis), which explained 72 of the variance. The concurrent validity of the A-ADAS-Cog was established using the A-MMSE score (r=-0.86), CDR Sum of Boxes score (CDR-SB; r=0.87), and global CDR score (CDR-Global; r=0.74). Finally, the A-ADAS-Cog has an excellent discriminating power in the diagnosis of AD (ROC area=0.92). A cut-off score of 10 (sensitivity=84 and specificity=91) is indicated for the screening of the AD. Overall, the results indicated that the A-ADAS-Cog is psychometrically reliable and valid and provides promising results for screening of dementia in Arabic speaking patients. |
Language | en |
Publisher | IOS Press |
Subject | Alzheimer's disease Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) Arabic version culture normative data reliability test adaptation validity |
Type | Article |
Pagination | 11-21 |
Issue Number | 1 |
Volume Number | 60 |
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