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AuthorShaker, Mohamed A.
AuthorYounes, Husam M.
Available date2024-02-27T11:15:58Z
Publication Date2015-11-10
Publication NameJournal of Controlled Release
Identifierhttp://dx.doi.org/10.1016/j.jconrel.2015.07.005
CitationShaker, M. A., & Younes, H. M. (2015). Photo-irradiation paradigm: mapping a remarkable facile technique used for advanced drug, gene and cell delivery. Journal of Controlled Release, 217, 10-26.
ISSN0168-3659
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84940379810&origin=inward
URIhttp://hdl.handle.net/10576/52322
AbstractUndoubtedly, the progression of photo-irradiation technique has provided a smart engineering tool for the state-of-the-art biomaterials that guide the biomedical and therapeutic domains for promoting the modern pharmaceutical industry. Many investigators had exploited such a potential technique to create/ameliorate numerous pharmaceutical carriers. These carriers show promising applications that vary from small drug to therapeutic protein delivery and from gene to living cell encapsulation design. Harmony between the properties of precisely engineered precursors and the formed network structure broadens the investigator's intellect for both brilliant creations and effective applications. As well, controlling photo-curing at the formulation level, through manipulating the absorption of light stimuli, photoinitiator system and photo-responsive precursor, facilitates the exploration of novel distinctive biomaterials. Discussion of utilizing different photo-curing procedures in designing/formulation of different pharmaceutical carriers is the main emphasis of this review. In addition, recent applications of these intelligent techniques in targeted, controlled, and sustained drug delivery with understanding of photo-irradiation concept and mechanism are illustrated.
Languageen
PublisherElsevier
SubjectBiomaterials
Drug delivery
Pharmaceutical carriers
Photo-irradiation
TitlePhoto-irradiation paradigm: Mapping a remarkable facile technique used for advanced drug, gene and cell delivery
TypeArticle
Pagination10-26
Volume Number217
ESSN1873-4995
dc.accessType Open Access


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