The Role of Apolipoproteins in the Commonest Cancers: A Review
التاريخ
2023-11-24المؤلف
Darwish, Nour M.Al-Hail, Mooza Kh
Mohamed, Youssef
Al Saady, Rafif
Mohsen, Sara
Zar, Amna
Al-Mansoori, Layla
Pedersen, Shona
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البيانات الوصفية
عرض كامل للتسجيلةالملخص
Apolipoproteins (APOs) are vital structural components of plasma lipoproteins that are involved in lipid metabolism and transport. Recent studies have reported an association between apolipoprotein dysregulation and the onset of a variety of human cancers; however, the role of certain APOs in cancer development remains unknown. Based on recent work, we hypothesize that APOs might be involved in the onset of cancer, with a focus on the most common cancers, including breast, lung, gynecological, colorectal, thyroid, gastric, pancreatic, hepatic, and prostate cancers. This review will focus on the evidence supporting this hypothesis, the mechanisms linking APOs to the onset of cancer, and the potential clinical relevance of its various inhibitors.
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