Histopathological risk assessment in multisite epithelial dysplasia: A meta-analysis.
المؤلف | Ferraz, Daniel Lobato Ferreira |
المؤلف | Dos Santos, Erison Santana |
المؤلف | Pedroso, Caique Mariano |
المؤلف | Silva, Brunno Santos de Freitas |
المؤلف | Kujan, Omar |
المؤلف | Salo, Tuula Anneli |
المؤلف | Malki, Mohammed I |
المؤلف | Juteau, Susanna |
المؤلف | Vargas, Pablo Agustin |
المؤلف | Lopes, Marcio Ajudarte |
المؤلف | Santos-Silva, Alan Roger |
تاريخ الإتاحة | 2024-07-09T05:08:52Z |
تاريخ النشر | 2024-06-30 |
اسم المنشور | Oral Diseases |
المعرّف | http://dx.doi.org/10.1111/odi.15052 |
الاقتباس | Ferraz, D. L. F., dos Santos, E. S., Pedroso, C. M., Silva, B. S. d. F., Kujan, O., Salo, T. A., Malki, M. I., Juteau, S., Vargas, P. A., Lopes, M. A., & Santos-Silva, A. R. (2024). Histopathological risk assessment in multisite epithelial dysplasia: A meta-analysis. Oral Diseases, 00, 1–9. https://doi.org/10.1111/odi.15052 |
الرقم المعياري الدولي للكتاب | 1354-523X |
الملخص | Histopathological grading of oral epithelial dysplasia (OED) is the current standard for stratifying cancer progression risk but is associated with subjectivity and variability. This problem is not commonly seen regarding the grading of epithelial dysplasia in other sites. This systematic review aims to compare grading systems for oral, anal, penile, and cervical epithelial dysplasia to determine their predictive accuracy for recurrence and malignant transformation (MT) outcomes. The review protocol was registered in PROSPERO (CRD42023403035) and was reported according to the PRISMA checklist. A comprehensive search was performed in the main databases and gray literature. The risk of bias in individual studies was analyzed using the Joanna Briggs Institute checklist for each study design. Forty-six studies were deemed eligible and included in this systematic review, of which 45 were included in the quantitative analysis. Meta-analysis revealed that the binary system demonstrated a higher predictive ability for MT/recurrence of OED compared to multilevel systems. Higher predictive accuracy of MT was also observed for binary grading systems in anal intraepithelial neoplasia. No significant difference was found between the current grading systems of epithelial dysplasia in different body parts. However, binary grading systems have shown better clinical outcomes. |
اللغة | en |
الناشر | John Wiley & Sons Ltd |
الموضوع | epithelial dysplasia histopathological grading intraepithelial neoplasia precancerous conditions systematic review |
النوع | Article Review |
ESSN | 1601-0825 |
الملفات في هذه التسجيلة
هذه التسجيلة تظهر في المجموعات التالية
-
أبحاث الطب [1382 items ]