Epidemiology of urinary tract infection in adults caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae - a case-control study from Qatar
المؤلف | Naushad, Vamanjore A. |
المؤلف | Purayil, Nishan K. |
المؤلف | Wilson, Godwin J. |
المؤلف | Chandra, Prem |
المؤلف | Joseph, Prakash |
المؤلف | Khalil, Zahida |
المؤلف | Zahid, Muhammad |
المؤلف | Kayakkool, Muhammed K. |
المؤلف | Shaik, NoorJahan |
المؤلف | Ayari, Basma |
المؤلف | Chalihadan, Sajid |
المؤلف | Elmagboul, Emad Basheir I. |
المؤلف | Doiphode, Sanjay H. |
تاريخ الإتاحة | 2024-07-22T09:19:58Z |
تاريخ النشر | 2022 |
اسم المنشور | IJID Regions |
المصدر | Scopus |
المعرّف | http://dx.doi.org/10.1016/j.ijregi.2022.05.001 |
الرقم المعياري الدولي للكتاب | 27727076 |
الملخص | Background: Community-acquired urinary tract infection (UTI) is the most common infection caused by extended-spectrum beta-lactamase (ESBL)-producing organisms. Aim: to estimate the prevalence of ESBL-UTI in adults and to identify potential risk factors that may predispose to ESBL-UTI. Methods: A retrospective study involving adult patients with UTI caused by ESBL-producing organisms was undertaken. Patients with UTI caused by non-ESBL-producing organisms represented the control group. Results: In total, 1100 UTI isolates were included in the study, 277 of which were ESBL positive. The prevalence rate was 25.2%. The mean age of patients was 55.87 years. On univariate analysis, prior history of UTI or ESBL-UTI, invasive urological procedure within preceding 3 months, hospital admission within preceding 3 months, and exposure to antibiotics were found to be significant risk factors for ESBL-UTI. On multi-variate analysis, use of cephalosporins [adjusted odds ratio (OR) 1.61, P=0.048], previous ESBL-UTI (adjusted OR 2.67, P<0.001), and invasive urological procedure in the preceding year (adjusted OR 1.61, P=0.022) were found to be independent risk factors for ESBL-UTI. Conclusions: In Qatar, the prevalence of ESBL-UTI in adults is modest. Recent exposure to antibiotics, previous ESBL-UTI and invasive urological procedures were found to be independent risk factors for ESBL-UTI. |
راعي المشروع | None. This study was approved by the Institutional Review Board of Medical Research Centre, Hamad Medical Corporation (Approval No. MRC-01-20-006). |
اللغة | en |
الناشر | Elsevier |
الموضوع | Antibiotics ESBL Extended-spectrum beta-lactamase Urinary tract infections |
النوع | Article |
الصفحات | 278-286 |
رقم المجلد | 3 |
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