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AuthorLiao, Zhengrui
AuthorYeoh, Yu-Kee
AuthorParumasivam, Thaigarajan
AuthorKoh, Wee Yin
AuthorAlrosan, Mohammad
AuthorAlu'datt, Muhammad H.
AuthorTan, Thuan-Chew
Available date2024-08-28T04:23:44Z
Publication Date2024
Publication NameRSC Advances
ResourceScopus
ISSN20462069
URIhttp://dx.doi.org/10.1039/d4ra02598a
URIhttp://hdl.handle.net/10576/58244
AbstractSuccinic (SUA), glutaric (GLA), pimelic (PA), suberic (SUBA), adipic (ADA), azelaic (AZA), and sebacic acids (SA) make up the majority of medium-chain dicarboxylic acids (MCDAs) with chain lengths of C4-C10, and are widely utilised in the chemical, food, textile, pesticide, pharmaceutical, and liquid crystal sectors. The MCDAs' two carboxyl groups provide them with an incredibly broad variety of applications. The focus of significant scientific research now is on the increasingly varied pharmacological effects of MCDAs. However, only a few studies have compared the biological characteristics of MCDAs in the contemporary pharmaceutical and cosmetic sectors and thoroughly examined the most recent research and marketing initiatives for MCDAs. This review's objective is to offer a thorough analysis of academic works on MCDAs, to assess the usefulness of these substances' chemical-pharmacological properties for use in the contemporary pharmaceutical and cosmetic industries, and to investigate the direction of their possible applications in these two disciplines. In addition, this review investigates how these compounds are metabolised in the human body.
Languageen
PublisherRoyal Society of Chemistry
SubjectChemical contamination
Liquid crystals
Pesticides
Textiles
Azelaic acid
Carboxyl groups
Chains length
Cosmetic industry
Dicarboxylic acid
Liquid-crystals
Pharmaceutical industry
Pharmacological properties
Scientific researches
Sebacic acid
Cosmetics
TitleMedium-chain dicarboxylic acids: chemistry, pharmacological properties, and applications in modern pharmaceutical and cosmetics industries
TypeArticle Review
Pagination17008-17021
Issue Number24
Volume Number14
dc.accessType Open Access


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