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Now showing items 31-38 of 38
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer
(
Elsevier Masson s.r.l.
, 2020 , Article)
Great strides have been made in triple negative breast cancer (TNBC) treatment, which represents 20% of total predicted annual US breast cancer (BC) cases. Despite the development of several therapeutics, TNBC patients ...
Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
(
Bentham Science Publishers
, 2020 , Article)
Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ...
Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells
(
MDPI
, 2020 , Article)
Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated ...
A comprehensive review on the antiviral activities of chalcones
(
Taylor and Francis Ltd.
, 2021 , Article)
Some viral outbreaks have plagued the world since antiquity, including the most recent COVID-19 pandemic. The continuous spread and emergence of new viral diseases have urged the discovery of novel treatment options that ...
Association between waterpipe smoking and obesity: Population-based study in Qatar
(
European Publishing
, 2022 , Article)
Introduction:
Over the past decade obesity prevalence has been increasing rapidly in the Gulf region (GR) including Qatar, becoming one of the major health issues in the region. Concomitantly, waterpipe (WP) smoking is ...
Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
(
Frontiers Media S.A.
, 2022 , Article)
Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ...
A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers
(
John Wiley and Sons Inc
, 2021 , Article)
Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ...
High-risk human papillomaviruses and Epstein–Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study
(
Springer Nature
, 2021 , Article)
Background: High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein–Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as ...