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المؤلفDargham, Soha
المؤلفNasrallah, Gheyath
المؤلفAl-Absi, Enas
المؤلفMohammed, Layla
المؤلفAl Disi, Rana
المؤلفNoufal, Mariam
المؤلفAbu-Raddad, Laith
تاريخ الإتاحة2018-02-07T07:26:27Z
تاريخ النشر2017-07-08
اسم المنشورSexually Transmitted Infections
المعرّفhttp://dx.doi.org/10.1136/sextrans-2017-053264.445
الاقتباسDargham S, Nasrallah G, Al-Absi E, et al P3.210 Estimating the antibody prevalence of herpes simplex virus type 2 among select middle east and north africa populations Sex Transm Infect 2017;93:A171.
الرقم المعياري الدولي للكتاب1368-4973
معرّف المصادر الموحدhttp://hdl.handle.net/10576/6243
الملخصIntroduction There are very limited data on herpes simplex virus type 2 (HSV-2) infection in the Middle East and North Africa (MENA). We examined the overall and age-specific HSV-2 antibody prevalence among select MENA populations currently residing in Qatar. Methods Sera were collected from blood donors attending Hamad Medical Corporation June 2013–2015. Specimens were screened for HSV-2 antibodies using HerpeSelect 2 ELISA IgG kits. All positive and equivocal specimens detecting presence of HSV-2 antibodies were retested for final HSV-2 status using Euroline Westernblot assays. Demographic information included nationality, age, and sex. Age was grouped into 8 bands:≤24, 25–29, 30–34, 35–39, 40–44, 45–49, 50–54, and ≥55. Age-specific trend of HSV-2 infection among Egyptian, Fertile Crescent (Iraq, Jordan, Lebanon, Palestine, and Syria) and Qatari nationals was described and assessed using the Cochran–Armitage test. Results Sera from 2165 blood donors were tested for HSV-2. Among 132 retested specimens, 66 were confirmed positive. Country-specific HSV-2 prevalence was measured at 5.5% (95% confidence interval (CI) 3.7%–8.2%) for Qataris, 4.5% (95%CI 1.9%–10.0%) for Iranians, 4.2% (95%CI 1.8%–9.5%) for Lebanese, 3.1% (95%CI 1.2%–7.7%) for Sudanese, 3.0% (95%CI 1.4%–6.4%) for Palestinians, 2.2% (95%CI 1.1%–4.3%) for Egyptians, 2.0% (95%CI 1.0%–5.0%) for Syrians, 1.0% (95%CI 0.3%–3.6%) for Jordanians, 0.7% (95%CI 0.1%–3.7%) for Yemenis, and 0.5% (95%CI 0.1%–2.8%) for Pakistanis. Age-specific HSV-2 prevalence was estimated for Egyptians, nationals of the Fertile Crescent, and Qataris. Overall, HSV-2 prevalence increased with age, but the trend was not always statistically significant in these populations. HSV-2 prevalence was significantly higher for females at 9.1% (95%CI 4.7%–16.9%) than males at 2.8% (95%CI 2.2%–3.6%) (χ2p-value<0.01). Conclusion HSV-2 prevalence among MENA nationals was found to be lower than that commonly found in other regions. However, these observed prevalence levels suggest unmet needs for sexual health and control of sexually transmitted infections (STIs) transmission. Programs need to be established to tackle STIs and their disease burden in this region.
اللغةen
الناشرBMJ Publishing Group
الموضوعherpes simplex virus
Antibody
Middle East
North Africa
العنوانP3. 210 Estimating the antibody prevalence of herpes simplex virus type 2 among select middle east and north africa populations
النوعConference Proceedings
الصفحات171
رقم العدد2
رقم المجلد93
ESSN1472-3263
dc.accessType Abstract Only


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