Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo.
Author | yalcin, huseyin c |
Available date | 2018-08-13T07:24:29Z |
Publication Date | 2018-06-13 |
Publication Name | Methods in Molecular Biology |
Identifier | http://dx.doi.org/10.1007/978-1-4939-7883-0_27 |
Citation | Yalcin H.C. (2018) Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo. In: Félix L. (eds) Teratogenicity Testing. Methods in Molecular Biology, vol 1797. Humana Press, New York, NY |
ISBN | 9781493978823 |
ISBN | 9781493978830 |
Abstract | Investigations of teratogenic effects of drugs generally involve testing the drug on animals and zebrafish embryo is a commonly used animal model for that purpose. In these studies, cardiovascular function of the animals needs to be evaluated to reveal the influence of exposure on the development of the cardiovascular system as well as on the growth of the whole animal. Here, relevant microscopy imaging and analysis protocols are described to calculate a variety of hemodynamic parameters for zebrafish embryos exposed to clinical drugs. |
Language | en |
Publisher | Humana Press |
Subject | zebrafish hemodynamics teratogenicity heart function microscopy blood flow |
Type | Book chapter |
Pagination | 487-495 |
Volume Number | 1797 |
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Biomedical Research Center Research [709 items ]