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Authoryalcin, huseyin c
Available date2018-08-13T07:24:29Z
Publication Date2018-06-13
Publication NameMethods in Molecular Biology
Identifierhttp://dx.doi.org/10.1007/978-1-4939-7883-0_27
CitationYalcin H.C. (2018) Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo. In: Félix L. (eds) Teratogenicity Testing. Methods in Molecular Biology, vol 1797. Humana Press, New York, NY
ISBN9781493978823
ISBN9781493978830
URIhttp://hdl.handle.net/10576/6827
AbstractInvestigations of teratogenic effects of drugs generally involve testing the drug on animals and zebrafish embryo is a commonly used animal model for that purpose. In these studies, cardiovascular function of the animals needs to be evaluated to reveal the influence of exposure on the development of the cardiovascular system as well as on the growth of the whole animal. Here, relevant microscopy imaging and analysis protocols are described to calculate a variety of hemodynamic parameters for zebrafish embryos exposed to clinical drugs.
Languageen
PublisherHumana Press
Subjectzebrafish
hemodynamics
teratogenicity
heart function
microscopy
blood flow
TitleHemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo.
TypeBook chapter
Pagination487-495
Volume Number1797
dc.accessType Abstract Only


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