Search
Now showing items 1-8 of 8
Brain Microstructural Changes Support Cognitive Deficits in Normal Children Born to HIVinfected Mothers
(2018 , Conference Proceedings)
Synopsis
In the current study, we evaluated the brain integrity [by mapping the fractional anisotropy (FA) and mean diffusivity (MD)] and neurocognitive
performance (NP) in normal children (NCI) born to HIV-infected ...
The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
(
SAGE Publications Ltd
, 2017 , Article)
Many microbial and plant-derived metabolites contribute to the production of inflammatory mediators and the expression of pro-inflammatory molecules. Ophiobolin A (OPA) is a fungal secondary metabolite produced by Bipolaris ...
The physiological effects of concurrent strength and endurance training sequence: A systematic review and meta-analysis.
(
Taylor & Francis
, 2017 , Article Review)
We conducted a systematic literature review and meta-analysis to assess the chronic effects of the sequence of concurrent strength and endurance training on selected important physiological and performance parameters, ...
Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model
(
MDPI AG
, 2018 , Article)
Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of oral anti-diabetic drugs, implicated in pleiotropic secondary cardioprotective effects. The aim of the study was to unveil the unknown and possible cardioprotective ...
In Vitro Analysis of Psoriasis Linked CARMA2sh Gene in Keratinocytes and Mouse Embryonic Stem Cells towards Developing a Murine Transgenic Model
(
American Association For Laboratory Animal Science
, 2017 , Poster)
Psoriasis is a debilitating skin disease affecting approximately 23% of
human population. Genome-wide association studies have identified
more than 40 susceptibility loci for psoriasis. CARMA2 proteins play a
major role ...
Single-Voxel H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD ) in humans at 7T using a 32-channel volume coil.
(
Wiley
, 2019 , Article)
Reliable monitoring of tissue nicotinamide adenine dinucleotide (NAD ) concentration may provide insights on its roles in normal and pathological aging. In the present study, we report a H MRS pulse sequence for the in ...
RAS-mediated oncogenic signaling pathways in human malignancies
(
Elsevier
, 2018 , Article Review)
Abnormally activated RAS proteins are the main oncogenic driver that governs the functioning of major signaling
pathways involved in the initiation and development of human malignancies. Mutations in RAS genes and
or its ...
Role of animal research in human malignancies
(
Elsevier
, 2019 , Book chapter)
Animal models are the central backbone in relation to providing the safety information of xenobiotics, the nature of chemicals present in the environment, and understanding the developmental process in disease pathogenesis ...