Toxic Effect Of Lannate On Cellular Defence System In Erythrocyte Of Rat

Abstract

Lannate 1 - methomyl was incubated with erythrocytes of rats at different concentrations. It has been observed that there was a decrease in the activities of superoxide dismutase and glutathione reductase after 1/2 and 16 hour of Lannate addition. There was also a decrease in the amount of glutathione. The inhibition of enzyme activities and the decrease in glutathione concentration were dose independent. The results suggest that Lannate toxicity might lead to haemolysis, oxidation of haemoglobin and finally induced erythropenia.