Academic: Recent submissions
Now showing items 21-40 of 29959
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Unraveling the Omega-3 Puzzle: Navigating Challenges and Innovations for Bone Health and Healthy Aging
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Omega-3 polyunsaturated fatty acids (ω-3 PUFAs, n-3 PUFAs), including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and alpha-linolenic acid (ALA), are essential polyunsaturated fats primarily obtained from fatty ... -
Cost-effectiveness analysis of genotype-guided optimization of major depression treatment in Qatar
( Taylor and Francis Ltd. , 2024 , Article)Background Pharmacogenetic testing improves the efficacy and safety of antidepressant pharmacotherapy for moderate-severe major depressive disorder by identifying genetic variations that influence medication metabolism, ... -
Real-World Data Presenting the Descriptive Analysis of the Use of Tyrosine Kinase Inhibitors (TKIs) Among Metastatic Non-Small-Cell Lung Cancer (mNSCLC) Patients in Qatar: A Nationwide Retrospective Cohort Study
( SAGE Publications Ltd , 2024 , Article)Background: There has been significant improvement in treating metastatic non-small-cell lung cancer (mNSCLC) over the past 2 decades. The aim of this study is to describe the use of tyrosine kinase inhibitors (TKIs) in ... -
A Novel Nano-Hydroxyapatite Agarose-Based Hydrogel for Biomimetic Remineralization of Demineralized Human Enamel: An in-vitro Study
( Dove Medical Press Ltd , 2024 , Article)Purpose: This study aims to investigate the biomimetic effect of agarose hydrogel loaded with enamel matrix derivative (EMD-agarose) alone or in combination with nano-hydroxyapatite (n-HA-EMD-agarose) on the remineralization ... -
Identification of novel hypertension biomarkers using explainable AI and metabolomics
( Springer , 2024 , Article)Background: The global incidence of hypertension, a condition of elevated blood pressure, is rising alarmingly. According to the World Health Organization's Qatar Hypertension Profile for 2023, around 33% of adults are ... -
Response to the Letter on "Plasma Sodium and Laboratory Parameters in Determining Complicated Appendicitis in Children"
( S. Karger AG , 2024 , Article)We are very grateful to the authors of the letter regarding our article, published in Medical Principles and Practice. We truly appreciate their comments and criticism. It is worthwhile knowing that it induced the interest ... -
Efficacy and safety of daratumumab for the treatment of refractory/relapsed multiple myeloma. A systematic review of meta-analyses
( SAGE Publications Ltd , 2025 , Article Review)Introduction: Several meta-analyses (MAs) of the efficacy and safety of daratumumab in refractory/relapsed multiple myeloma (RRMM) exist. They include different types of populations, Daratumumab regimens, and outcomes. ... -
Circulating Cancer Stem Cells; Role in Cancer Prognosis, Metastasis and Targeted Therapy
( Elsevier , 2024 , Book chapter)Circulating Cancer Stem Cells (CCSCs) constitute a distinctive category of cancer cells that play pivotal roles in shaping multiple facets of the cancer continuum, spanning from the initiation and progression of oncogenesis ... -
The pharmacologic evolution of anticoagulants: From serendipity to precision therapy
( Elsevier , 2025 , Other)[N/A] -
Engineered Anti-Microbial Peptides Inhibit Cell Viability, Promote Apoptosis, and Induce Cell Cycle Arrest in SW620 Human Colon Adenocarcinoma Cells.
( Elsevier , 2025 , Article)Colorectal cancer (CRC) is one of the most common malignancies worldwide, and despite advances in treatment, there remains a critical need for novel therapeutic approaches. Recently, anti-microbial peptides (AMPs) have ... -
Reported Postoperative Surgical Site Infections in Tertiary Care Hospitals, Systematic Review of Recent Literature.
( Elsevier , 2025 , Article)The objective of this systematic review is to evaluate the patterns of postsurgical site infections, pre-surgical antibiotics prophylaxis, and related clinical outcomes in the recently published literature. This systematic ... -
Efficacy and Safety of Ivonescimab in the Treatment of Advanced Non-small Cell Lung Cancer (NSCLC): A Systematic Review
( Springer Nature , 2025 , Article)This systematic review critically evaluates the safety and efficacy of the novel drug Ivonescimab in the treatment of advanced and metastatic non-small cell lung cancer (NSCLC). Ivonescimab showed promising antitumor ... -
Unraveling the proteomic signatures of coronary artery disease and hypercholesterolemia.
( The Association of Basic Medical Sciences , 2024 , Article)Atherosclerosis, a leading cause of coronary artery disease (CAD), is heavily influenced by hypercholesterolemia (HC). Proteomics research has shown promise in identifying biological markers for CAD diagnosis and prognosis. ... -
Would Artificial Intelligence Improve the Quality of Care of Patients With Rare Diseases?
( Innovative Healthcare Institute , 2024 , Article)Rare diseases are characterized by low prevalence, they affect 4-5 patients per 10,000 people, which results in a lack of knowledge, guidelines, training, and diagnostic complexities among clinicians. This significantly ... -
Inflammation-Modulating Biomedical Interventions for Diabetic Wound Healing: An Overview of Preclinical and Clinical Studies
( American Chemical Society , 2024 , Article Review)A diabetic wound exemplifies the challenge of chronic, nonhealing wounds. Elevated blood sugar levels in diabetes profoundly disrupt macrophage function, impairing crucial activities such as phagocytosis, immune response, ... -
Automating Prostate Cancer Grading: A Novel Deep Learning Framework for Automatic Prostate Cancer Grade Assessment using Classification and Segmentation.
( Springer Nature , 2025 , Article)Prostate Cancer (PCa) is the second most common cancer in men and affects more than a million people each year. Grading prostate cancer is based on the Gleason grading system, a subjective and labor-intensive method for ... -
Against the Grain: Consumer's Purchase Habits and Satisfaction with Gluten-Free Product Offerings in European Food Retail
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Across the world and within Europe, a growing number of consumers are choosing to buy gluten-free products. Motivations for a gluten-free diet and the consequences of consuming gluten are varied, from a medical necessity ... -
The apoptotic and anti-proliferative effects of Neosetophomone B in T-cell acute lymphoblastic leukaemia via PI3K/AKT/mTOR pathway inhibition
( John Wiley and Sons Inc , 2025 , Article)The phosphatidylinositol 3-kinase/Protein Kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signalling pathway is pivotal in various cancers, including T-cell acute lymphoblastic leukaemia (T-ALL), a particularly ... -
Evaluating the appropriateness and the factors associated with sodium-glucose co-transporter 2 inhibitors prescribing in a Middle Eastern country: a cross-sectional study
( Springer Science and Business Media Deutschland GmbH , 2025 , Article)Background: Sodium glucose co-transporter 2 inhibitors (SGLT2is) are a novel class of oral antidiabetic drugs (ADDs). Studies evaluating the appropriateness of SGLT2is prescribing, and the factors associated with their ...
