Biomedical Sciences: المرسلات الحديثة
السجلات المعروضة 1 -- 20 من 796
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Qatar’s genetic counseling landscape: Current insights and future prospects
( Elsevier , 2024 , Article)Genetic counseling is a dynamic and rapidly growing field. In Qatar, the significance of genetic counseling is underscored by the distinctive demographic characteristics of the population, including elevated rates of ... -
Seroprevalence and Distribution of Toxoplasma gondii Infections among Patients in the West Bank, Palestine (2017-2021)
( American Society of Tropical Medicine and Hygiene , 2024 , Article)Toxoplasmosis is a zoonotic disease caused by the obligate intracellular protozoan Toxoplasma gondii. The current study assessed the seroepidemiological status and risk factors of T. gondii in the West Bank, Palestine. We ... -
Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey
( BMJ Publishing Group , 2024 , Article)Objectives Scant data are available on syphilis infection within migrant populations worldwide and in the population of the Middle East and North Africa region. This study investigated the prevalence of both lifetime and ... -
gnas Knockdown Induces Obesity and AHO Features in Early Zebrafish Larvae
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)GNAS (Guanine Nucleotide-Binding Protein, Alpha Stimulating) is a complex gene that encodes the alpha subunit of the stimulatory G protein (Gsα), critical for signaling through various G protein-coupled receptors. Inactivating ... -
Mechanical jejunal obstruction caused by a migrated intragastric balloon: a case report
( Oxford University Press , 2024 , Article)An intragastric balloon is often used as a temporary solution for weight loss. It is endoscopically placed into the stomach and filled with air or saline to encourage fullness and reduce meal intake. A 23-year-old female ... -
Artificial blood-hope and the challenges to combat tumor hypoxia for anti-cancer therapy
( Springer Science and Business Media Deutschland GmbH , 2025 , Article Review)The blood plays a vital role in the human body and serves as an intermediary between various physiological systems and organs. White blood cells, which are a part of the immune system, defend against infections and regulate ... -
Metabolic signatures of combined exercise and fasting: an expanded perspective on previous telomere length findings
( Frontiers Media SA , 2024 , Article)Introduction: Aging is a complex process marked by a gradual decline in physiological function and increased susceptibility to diseases. Telomere length is frequently regarded as one of the primary biomarkers of aging. ... -
Curcumin as a novel therapeutic candidate for cancer: can this natural compound revolutionize cancer treatment?
( Frontiers Media SA , 2024 , Article Review)Cancer remains one of the leading causes of death worldwide. Despite advances in medical treatments, current therapeutic strategies, including radiotherapy, chemotherapy, targeted therapy, and surgical resection, have not ... -
Factor V Leiden (R506Q), Prothrombin G20210A, and MTHFR C677T Variants and Thrombophilia in Qatar Biobank Participants: A Case Control Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Background: Thrombophilia, a predisposition to develop blood clots, is very common and can have serious sequelae. Aim: This study aimed to determine the prevalence of three thrombophilia-related genetic variants-factor V ... -
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
( Korean Tissue Engineering and Regenerative Medicine Society , 2025 , Article)Background: Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cells (MSCs) secrete Factor H and express CD59 to protect themselves from complement-mediated ... -
Unraveling the Omega-3 Puzzle: Navigating Challenges and Innovations for Bone Health and Healthy Aging
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Omega-3 polyunsaturated fatty acids (ω-3 PUFAs, n-3 PUFAs), including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and alpha-linolenic acid (ALA), are essential polyunsaturated fats primarily obtained from fatty ... -
Identification of novel hypertension biomarkers using explainable AI and metabolomics
( Springer , 2024 , Article)Background: The global incidence of hypertension, a condition of elevated blood pressure, is rising alarmingly. According to the World Health Organization's Qatar Hypertension Profile for 2023, around 33% of adults are ... -
Unraveling the proteomic signatures of coronary artery disease and hypercholesterolemia.
( The Association of Basic Medical Sciences , 2024 , Article)Atherosclerosis, a leading cause of coronary artery disease (CAD), is heavily influenced by hypercholesterolemia (HC). Proteomics research has shown promise in identifying biological markers for CAD diagnosis and prognosis. ... -
Inflammation-Modulating Biomedical Interventions for Diabetic Wound Healing: An Overview of Preclinical and Clinical Studies
( American Chemical Society , 2024 , Article Review)A diabetic wound exemplifies the challenge of chronic, nonhealing wounds. Elevated blood sugar levels in diabetes profoundly disrupt macrophage function, impairing crucial activities such as phagocytosis, immune response, ... -
Evaluating the Effects of BSA-Coated Gold Nanorods on Cell Migration Potential and Inflammatory Mediators in Human Dermal Fibroblasts
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Albumin-coated gold nanoparticles display potential biomedical applications, including cancer research, infection treatment, and wound healing; however, elucidating their interaction with normal cells remains an area with ... -
Enhancing Influenza Detection through Integrative Machine Learning and Nasopharyngeal Metabolomic Profiling: A Comprehensive Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Background/Objectives: Nasal and nasopharyngeal swabs are commonly used for detecting respiratory viruses, including influenza, which significantly alters host cell metabolites. This study aimed to develop a machine learning ... -
Detached pyloric gland adenoma of gallbladder: A case report and review of literature.
( Wiley , 2024 , Article)Vigilant intraoperative inspection is crucial during gallbladder surgery to detect any abnormal tissue including the rare pyloric gland adenomas, which can be easily missed. Thorough examination and removal of unusual lymph ... -
Gut Microbiota–Tumor Microenvironment Interactions: Mechanisms and Clinical Implications for Immune Checkpoint Inhibitor Efficacy in Cancer
( Dove Medical Press , 2025 , Article)Cancer immunotherapy has transformed cancer treatment in recent years, with immune checkpoint inhibitors (ICIs) emerging as a key therapeutic approach. ICIs work by inhibiting the mechanisms that allow tumors to evade ... -
Computational insights into irinotecan's interaction with UBE2I in ovarian and endometrial cancers
( Elsevier , 2024 , Article)Endometrial and Ovarian cancers are two highly prevalent and fatal reproductive diseases with poor prognoses among women. Elevated estrogen levels in Ovarian Cancer (OC) stimulate the endometrium, causing Endometrial Cancer ... -
Association Between Vitamin D Receptor BsmI Polymorphism and Low Bone Mineral Density in Postmenopausal Women in the MENA Region
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Background/Objectives: Low bone mineral density increases the risk of bone fractures, and this condition is especially common in postmenopausal women. Genetic factors significantly influence bone mineral density. This ...
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