Browsing by Author "Dhulkifle, Hevna"
Now showing items 1-3 of 3
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6-Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation
Dhulkifle, Hevna; Sayed, Tahseen S.; Abunada, Hanan H.; Abulola, Sara M.; Alhoshani, Ali; Korashy, Hesham M.; Maayah, Zaid H.... more authors ... less authors ( American Chemical Society (ACS) , 2023 , Article)Patients with sepsis are at a high risk of morbidity and mortality due to multiple organ injuries caused by pathological inflammation. Although sepsis is accompanied by multiple organ injuries, acute renal injury is a ... -
Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders
Dhulkifle, Hevna; Diab, Mohammad Issam; Algonaiah, Majed; Korashy, Hesham M.; Maayah, Zaid H. ( American Chemical Society (ACS) , 2024 , Article)Bromodomain and extra-terminal domain proteins (BET proteins) are epigenetic reader proteins that have been implicated in regulating gene expression through binding to chromatin and interaction with transcription factors. ... -
Influence of the Aryl Hydrocarbon Receptor Activating Environmental Pollutants on Autism Spectrum Disorder
Dhulkifle, Hevna; Agouni, Abdelali; Zeidan, Asaad; Al-Kuwari, Mohammed Saif; Parray, Aijaz; Tolefat, Mohamed; Korashy, Hesham M.... more authors ... less authors ( MDPI , 2021 , Article Review)Autism spectrum disorder (ASD) is an umbrella term that includes many different disorders that affect the development, communication, and behavior of an individual. Prevalence of ASD has risen exponentially in the past ...