• A population study of clinically actionable genetic variation affecting drug response from the Middle East 

      Jithesh, Puthen Veettil; Abuhaliqa, Mohammed; Syed, Najeeb; Ahmed, Ikhlak; El Anbari, Mohammed; ... more authors ( Nature Research , 2022 , Article)
      Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is ...
    • Qatar genome: Insights on genomics from the Middle East 

      Mbarek, Hamdi; Devadoss Gandhi, Geethanjali; Selvaraj, Senthil; Al-Muftah, Wadha; Badji, Radja; ... more authors ( Wiley , 2022 , Article)
      Despite recent biomedical breakthroughs and large genomic studies growing momentum, the Middle Eastern population, home to over 400 million people, is underrepresented in the human genome variation databases. Here we ...
    • The QChip1 knowledgebase and microarray for precision medicine in Qatar 

      Rodriguez-Flores, Juan L.; Messai-Badji, Radja; Robay, Amal; Temanni, Ramzi; Syed, Najeeb; ... more authors ( Nature Research , 2022 , Article)
      Risk genes for Mendelian (single-gene) disorders (SGDs) are consistent across populations, but pathogenic risk variants that cause SGDs are typically population-private. The goal was to develop "QChip1," an inexpensive ...