Browsing by Author "Maltesen, Raluca Georgiana"
Now showing items 1-4 of 4
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Characterising Alzheimer's disease through integrative NMR- and LC-MS-based metabolomics
Jonas Ellegaard, Nielsen; Maltesen, Raluca Georgiana; Havelund, Jesper F.; Færgeman, Nils J.; Gotfredsen, Charlotte Held; Vestergård, Karsten; Kristensen, Søren Risom; Pedersen, Shona... more authors ... less authors ( Elsevier , 2021 , Article)BackgroundAlzheimer's Disease (AD) is a complex and multifactorial disease and novel approaches are needed to illuminate the underlying pathology. Metabolites comprise the end-product of genes, transcripts, and protein ... -
Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics
Pedersen, Shona; Jensen, Katrine Papendick; Honoré, Bent; Kristensen, Søren Risom; Pedersen, Camilla Holm; Szejniuk, Weronika Maria; Maltesen, Raluca Georgiana; Falkmer, Ursula... more authors ... less authors ( BMC , 2022 , Article)Background: Early detection of small cell lung cancer (SCLC) crucially demands highly reliable markers. Growing evidence suggests that extracellular vesicles carry tumor cell-specific cargo suitable as protein markers in ... -
Identifying metabolic alterations in newly diagnosed small cell lung cancer patients
Shona, Pedersen; Hansen, Joachim Bavnhøj; Maltesen, Raluca Georgiana; Szejniuk, Weronika Maria; Andreassen, Trygve; Falkmer, Ursula; Kristensen, Søren Risom... more authors ... less authors ( Elsevier , 2021 , Article)BackgroundSmall cell lung cancer (SCLC) is a malignant disease with poor prognosis. At the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is based on imaging, histopathology, and ... -
Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways
Nielsen, Jonas Ellegaard; Honoré, Bent; Vestergård, Karsten; Maltesen, Raluca Georgiana; Christiansen, Gunna; Bøge, Anna Uhd; Kristensen, Søren Risom; Pedersen, Shona... more authors ... less authors ( Nature Research , 2021 , Article)Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging ...