Browsing by Author "Nielsen, Jonas B."

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    • Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants 

      Aragam, Krishna G.; Jiang, Tao; Goel, Anuj; Kanoni, Stavroula; Wolford, Brooke N.; ... more authors ( Nature Research , 2022 , Article)
      The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) ...

    • Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis 

      Hindy, George; Tyrrell, Daniel J.; Vasbinder, Alexi; Wei, Changli; Presswalla, Feriel; ... more authors ( American Society for Clinical Investigation , 2022 , Article)
      People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which ...