• Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy 

      Bhat, Ajaz A.; Nisar, Sabah; Singh, Mayank; Ashraf, Bazella; Masoodi, Tariq; ... more authors ( Wiley , 2022 , Article Review)
      Colorectal cancer (CRC) is a predominant life-threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment ...
    • Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy 

      Bhat, A.A.; Bhat, Ajaz A.; Nisar, Sabah; Maacha, Selma; Carneiro-Lobo, Tatiana Correa; ... more authors ( BMC , 2021 , Article Review)
      Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ...
    • Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance. 

      Maacha, Selma; Bhat, Ajaz A; Jimenez, Lizandra; Raza, Afsheen; Haris, Mohammad; ... more authors ( Springer Verlag , 2019 , Article)
      The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor ...
    • High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines 

      Rinchai, Darawan; Deola, Sara; Zoppoli, Gabriele; Kabeer, Basirudeen Syed Ahamed; Taleb, Sara; ... more authors ( American Association for the Advancement of Science , 2022 , Article)
      Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ...