Browsing by Author "Gossage S.J."
Now showing items 1-2 of 2
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A novel human pain insensitivity disorder caused by a point mutation in ZFHX2
Habib A.M.; Matsuyama A.; Okorokov A.L.; Santana-Varela S.; Bras J.T.; Aloisi A.M.; Emery E.C.; Bogdanov Y.D.; Follenfant M.; Gossage S.J.; Gras M.; Humphrey J.; Kolesnikov A.; Le Cann K.; Li S.; Minett M.S.; Pereira V.; Ponsolles C.; Sikandar S.; Torres J.M.; Yamaoka K.; Zhao J.; Komine Y.; Yamamori T.; Maniatis N.; Panov K.I.; Houlden H.; Ramirez J.D.; Bennett D.L.H.; Marsili L.; Bachiocco V.; Wood J.N.; Cox J.J.... more authors ... less authors ( Oxford University Press , 2018 , Article)Chronic pain is a major global public health issue causing a severe impact on both the quality of life for sufferers and the wider economy. Despite the significant clinical burden, little progress has been made in terms ... -
Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
Habib A.M.; Okorokov A.L.; Hill M.N.; Bras J.T.; Lee M.-C.; Li S.; Gossage S.J.; van Drimmelen M.; Morena M.; Houlden H.; Ramirez J.D.; Bennett D.L.H.; Srivastava D.; Cox J.J.... more authors ... less authors ( Elsevier Ltd , 2019 , Article)The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally ...