Browsing by Author "Buddenkotte J."
Now showing items 1-4 of 4
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Interleukin-4 and interleukin-13 evoke scratching behaviour in mice
Campion M.; Smith L.; Gatault S.; Métais C.; Buddenkotte J.; Steinhoff M.... more authors ... less authors ( Blackwell Publishing Ltd , 2019 , Article)Persistent and relapsing itch commonly manifests in inflammatory skin disorders such as atopic dermatitis (AD). AD pathogenesis is driven by interleukin-4 (IL-4) and interleukin-13 (IL-13). Dupilumab, a monoclonal antibody ... -
Protein expression profiling identifies key proteins and pathways involved in growth inhibitory effects exerted by guggulsterone in human colorectal cancer cells
Leo R.; Therachiyil L.; Siveen S.K.; Uddin S.; Kulinski M.; Buddenkotte J.; Steinhoff M.; Krishnankutty R.... more authors ... less authors ( MDPI AG , 2019 , Article)Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such ... -
Role of mast cells and basophils in pruritus
Steinhoff M.; Buddenkotte J.; Lerner E.A. ( Blackwell Publishing Ltd , 2018 , Article Review)To protect our body systems, there is a constant interactive conversation between the skin nervous and immune system. Important elements of this conversation in the skin include mast cells, basophils, and sensory nerve ... -
Understanding the Burden of Atopic Dermatitis in Africa and the Middle East
Al-Afif K.A.M.; Buraik M.A.; Buddenkotte J.; Mounir M.; Gerber R.; Ahmed H.M.; Tallman A.M.; Steinhoff M.... more authors ... less authors ( Springer Healthcare , 2019 , Article Review)Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intensely pruritic lesions. The prevalence of atopic dermatitis is increasing in developing regions, including Africa and the Middle East. ...