Browsing by Subject "controlled study"
Now showing items 21-40 of 45
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Functional connectivity alterations in epilepsy from resting-state functional MRI
( Public Library of Science , 2015 , Article)The study of functional brain connectivity alterations induced by neurological disorders and their analysis from resting state functional Magnetic Resonance Imaging (rfMRI) is generally considered to be a challenging task. ... -
Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
( Elsevier B.V. , 2021 , Article)Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ... -
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
( Elsevier B.V. , 2016 , Article)This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ... -
How Red, Blue, and Green are Affectively Judged
( John Wiley and Sons Ltd , 2016 , Article)The present study aimed at examining how the colors red, blue, and green were affectively judged through three variables: dominance, arousal, and pleasure. All participants were exposed to red, blue, green, and white ... -
Impact of a pharmacist-delivered discharge and follow-up intervention for patients with acute coronary syndromes in Qatar: A study protocol for a randomised controlled trial
( BMJ Publishing Group , 2016 , Article)Introduction: Acute coronary syndrome (ACS) is one of the leading causes of morbidity and mortality worldwide. Secondary cardiovascular risk reduction therapy (consisting of an aspirin, a ?-blocker, an ACE inhibitor or an ... -
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
( Blackwell Publishing Ltd , 2016 , Article)Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ... -
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
( Elsevier , 2023 , Article)Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. Objective: In this study, we ... -
Intercalation of ionic liquids into bentonite: Swelling and rheological behaviors
( Elsevier B.V. , 2016 , Article)In this study, direct intercalation of three different green ionic liquids (ILs) having different salt and cation sizes into bentonite interlayer is investigated. The ILs covered in this study are: 1-hexyl-3-methylimidazolium ... -
Isolation and Physicochemical Characterization of Laccase from Ganoderma lucidum-CDBT1 Isolated from Its Native Habitat in Nepal
( Hindawi Limited , 2016 , Article)At present, few organisms are known to and capable of naturally producing laccases and white rot fungi are one such group. In the present study, three fungal species, namely, Ganoderma lucidum-CDBT1, Ganoderma japonicum, ... -
Magnetic mesoporous nanospheres anchored with LyP-1 as an efficient pancreatic cancer probe
( Elsevier Ltd , 2017 , Article)Immobilization of a ligand that selectively interacts with cancer cells to nanomaterials can enhance their diagnostic and therapeutic efficiency. In this study, we firstly demonstrate the high expression of receptor for ... -
Metronidazole in conjunction with penicillin neither prevents recurrence nor enhances recovery from peritonsillar abscess when compared with penicillin alone: A prospective, double-blind, randomized, placebo-controlled trial
( Oxford University Press , 2016 , Article)Objectives The objectives of this study were to evaluate the efficacy of metronidazole in conjunction with penicillin in preventing the recurrence of peritonsillar abscess (PTA) and to learn whether metronidazole enhances ... -
Monitoring non-parametric profiles using adaptive EWMA control chart
( Nature Research , 2022 , Article)To monitor the quality of a process in statistical process control (SPC), considering a functional relationship between a dependent variable and one or more independent variables (which is denoted as profile monitoring) ... -
Mortality prediction utilizing blood biomarkers to predict the severity of COVID-19 using machine learning technique
( MDPI , 2021 , Article)Healthcare researchers have been working on mortality prediction for COVID-19 patients with differing levels of severity. A rapid and reliable clinical evaluation of disease intensity will assist in the allocation and ... -
Multiscale structural evolution of citrate-triggered intrafibrillar and interfibrillar mineralization in dense collagen gels
( Academic Press Inc. , 2020 , Article)The mineralized extracellular matrix of bone is an organic?inorganic nanocomposite consisting primarily of carbonated hydroxyapatite, fibrous type I collagen, noncollagenous proteins, proteoglycans, and diverse biomolecules ... -
Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy
( Public Library of Science , 2015 , Article)Enhanced expression and activity of the Na+/H+ exchanger isoform 1 (NHE1) has been implicated in cardiomyocyte hypertrophy in various experimental models. The upregulation of NHE1 was correlated with an increase in osteopontin ... -
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
( Dove Medical Press Ltd. , 2020 , Article)Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ... -
NiFe2O4/poly(ethylene glycol)/lipid-polymer hybrid nanoparticles for anti-cancer drug delivery
( Royal Society of Chemistry , 2020 , Article)The present study reports the fabrication of hybrid nanoparticles consisting of nickel ferrite (NFO) for anti cancer drug delivery. The hybrid system was formulated from poly(vinyl alcohol)/stearic acid with PEG containing ... -
Prevalence of microplastics in the marine waters of Qatar
( Elsevier Ltd , 2016 , Article)Microplastics are firmly recognized as a ubiquitous and growing threat to marine biota and their associated marine habitats worldwide. The evidence of the prevalence of microplastics was documented for the first time in ... -
Ranitidine Impairs Bone Healing and Implant Osseointegration in Rats' Tibiae
( W.B. Saunders , 2020 , Article)Purpose: Ranitidine has been found to have an impact on bone metabolism by suppressing osteoclastogenesis. We hypothesized that the use of ranitidine would impair bone healing and implant osseointegration. This study ... -
The effect of aging on the bone healing properties of blood plasma
( Elsevier Ltd , 2021 , Article)Objectives: Age-related changes in blood composition have been found to affect overall health. Thus, this study aimed to understand the effect of these changes on bone healing by assessing how plasma derived from young and ...