Browsing by Subject "ADMET prediction"

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Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence

Bassi, Marta; Bilel, Sabrine; Tirri, Micaela; Corli, Giorgia; Di Rosa, Fabiana; Gregori, Adolfo; Alkilany, Alaaldin M.; Rachid, Ousama; Roda, Elisa; Zauli, Giorgio; Locatelli, Carlo Alessandro; Marti, Matteo... more authors ... less authors ( Springer Nature , 2024 , Article)
Rationale: The 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT, known online as “Moxy”) is a new psychedelic tryptamine first identified on Italian national territory in 2014. Its hallucinogen effects are broadly ...
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports

Marta, Bassi; Bilel, Sabrine; Tirri, Micaela; Corli, Giorgia; Di Rosa, Fabiana; Gregori, Adolfo; Alkilany, Alaaldin M.; Rachid, Ousama; Roda, Elisa; De Luca, Fabrizio; Papa, Pietro; Buscaglia, Eleonora; Zauli, Giorgio; Locatelli, Carlo Alessandro; Marti, Matteo... more authors ... less authors ( Elsevier , 2024 , Article)
The 3,4-methylenedioxy-alpha-pyrrolidinohexanophenone (MDPHP) is a synthetic cathinone closely related to 3,4-methylenedioxypyrovalerone (MDPV), one of the most common synthetic cathinones present in the “bath salts”. MDPHP ...