Browsing by Subject "Immune checkpoint inhibitors"

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A Chromosome 9p24.1 Amplification in Colorectal Cancer with Metastases to the Kidney and Adrenal Gland: A Case Report

Paric, Ana; Karan-Krizanac, Dragana; Saric, Ivan; Vranic, Semir ( karger , 2023 , Article)
Colorectal cancer (CRC) is the third leading cause of mortality worldwide. The Food and Drug Administration recently designated pembrolizumab, an immune checkpoint inhibitor (ICI) against a programmed death-1 receptor, as ...
Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials.

Elmakaty, Ibrahim; Abdo, Ruba; Elsabagh, Ahmed; Elsayed, Abdelrahman; Malki, Mohammed Imad ( BioMed Central , 2023 , Article)
Triple-Negative Breast Cancer (TNBC) is a lethal subtype of breast cancer with limited treatment options. The purpose of this Network Meta-Analysis (NMA) is to compare the efficacy and safety of inhibitors of programmed ...
Comprehensive analysis of cancers of unknown primary for the biomarkers of response to immune checkpoint blockade therapy

Gatalica, Zoran; Xiu, Joanne; Swensen, Jeff; Vranic, Semir ( Elsevier Ltd , 2018 , Article)
Background: Cancer of unknown primary (CUP) accounts for approximately 3% of all malignancies. Avoiding immune destruction is a major cancer characteristic and therapies aimed at immune checkpoint blockade are in use for ...