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Now showing items 4902-4921 of 48376
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Clinical and molecular characterization of hidradenitis suppurativa: a practical framework for novel therapeutic targets.
( Karger Publishers , 2023 , Report)Background: The pathophysiological picture underlying hidradenitis suppurativa (HS) and its syndromic forms is still patchy, thus presenting a great challenge for dermatologists and researchers since just by better ... -
CLINICAL AND PHARMACOECONOMIC ANALYSES OF CDK4/6 INHIBITORS USE IN STAGE IV BREAST CANCER FEMALES IN THE STATE OF QATAR: A COMPARATIVE RETROSPECTIVE OBSERVATIONAL STUDY WITH COST-EFFECTIVENESS AND COST-UTILITY ANALYSES
(2021 , Master Thesis)Introduction: Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are indicated in the first-line treatment of hormonal receptor positive and HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although phase III ... -
Clinical And Pharmacokinetic Evaluation Of Optimal Monitoring Parameters And Sampling Schemes For Vancomycin Therapeutic Drug Monitoring In Qatar
(2018 , Master Thesis)Background: Therapeutic drug monitoring (TDM) of vancomycin has been proven to maximize therapeutic outcomes and minimize toxicity when conducted appropriately. The quality of vancomycin TDM services in many settings ... -
Clinical and Pharmacokinetic Outcomes of Peak–Trough-Based Versus Trough-Based Vancomycin Therapeutic Drug Monitoring Approaches: A Pragmatic Randomized Controlled Trial
( Springer-Verlag France , 2019 , Article)Background Vancomycin therapeutic drug monitoring (TDM) is based on achieving 24-h area under the concentration–time curve to minimum inhibitory concentration cure breakpoints (AUC24/MIC). Approaches to vancomycin TDM ... -
Clinical assessment and risk stratification for prehospital use of methoxyflurane versus standard analgesia in adult patients with trauma pain
( PMC , 2023 , Article)Oligoanalgesia, the undertreatment of trauma-related pain using standard analgesics in prehospital and emergency departments, has been extensively documented as one of the major challenges affecting the effective treatment ... -
Clinical benefits and costs of an outpatient parenteral antimicrobial therapy service
( Elsevier , 2021 , Article)BackgroundThe enrolment of patients to an outpatient parenteral antimicrobial therapy (OPAT) service can be a means of mitigating financial burdens related to the provision of care and optimisation of hospital bed management. ... -
Clinical characteristics of 51,815 patients presenting with positive and negative SARS-CoV-2 swab results in primary health care settings: Priority populations for vaccination
( Elsevier , 2021 , Article)We read with interest Brendish et al. study on the comparison between patients with SARS-CoV-2 positive and negative swab results.1 The study compared the clinical characteristics of adult hospitalised patients with ... -
Clinical course and short-term outcome of postsplenectomy reactive thrombocytosis in children without myeloproliferative disorders: A single institutional experience from a developing country.
( Public Library of Science , 2020 , Article)To evaluate the clinical outcome and complications in the pediatric population who had splenectomy at our institution, emphasizing the incidence of postplenectomy reactive thrombocytosis (RT) and its clinical significance ... -
Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar.
( Elsevier , 2018 , Article)Clinical Exome Sequencing (CES) has increasingly become a popular diagnostic tool in patients suffering from genetic disorders that are clinically and genetically complicated. Myeloproliferative Neoplasms (MPNs) is an ... -
Clinical Implications of COVID-19 Presence in CSF: Systematic Review of Case Reports
( MDPI , 2022 , Article Review)This systematic review focused on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients that had detected SARS-CoV-2 virus in cerebrospinal fluid (CSF). A systematic literature search was carried out in ... -
Clinical Information System: Measuring End-User Satisfaction in a Governmental Hospital in Qatar
(2020 , Professional Masters Project)Clinical services in hospitals are too diversified and include different kinds of care patient needs. To be efficient, clinical services need to be supported by a promising clinical information system. As we did not find ... -
Clinical Internship: From Practice to Virtual
( Qatar University , 2020 , Video) -
Clinical manifestations associated with acute viral gastroenteritis pathogens among pediatric patients in Qatar.
( Wiley , 2021 , Article)Acute gastroenteritis (AGE) remains a significant cause of diarrhea that affects children worldwide. It is usually caused by viral agents, including rotavirus (RV), norovirus (NoV), adenovirus (AdV), astrovirus (AstV), and ... -
Clinical outcomes of high-intensity doses of atorvastatin in patients with acute coronary syndrome: A retrospective cohort study using real-world data
( Blackwell Publishing Ltd , 2021 , Article)Aims: To compare the effectiveness and safety of 2 high-intensity atorvastatin doses (40 mg vs 80 mg) among acute coronary syndrome (ACS) patients. Methods: This retrospective observational cohort study using real-world ... -
Clinical outcomes of Pfizer-BioNTech COVID-19 vaccine in children and adolescents: A systematic review
( John Wiley and Sons Inc , 2022 , Article Review)Background & Aims: The BioNTech-Pfizer vaccine is the only vaccine offered to children among all available vaccines. However, limited evidence is available about the clinical outcomes of COVID-19 vaccines, especially among ... -
The Clinical Pharmacist-Led Consultation for Infectious Diseases in Guizhou Province, China: A Survey Among Hospital Pharmacies
(2020 , Article)Background: As antimicrobial resistance became an increasing threat to global public health, Clinical Pharmacist-led Consultation (CPC) for Infectious Diseases (ID) was developed in China. We conducted a survey among ... -
Clinical pharmacists’ interventions for preventing adverse events in critically ill neonates in Qatar: an economic impact analysis
( Springer Nature , 2024 , Article)Objective: This study aimed to assess the overall economic impact of clinical pharmacist interventions in the neonatal ICU (NICU) in Qatar. Methods: A retrospective review of neonates’ records was performed over a 3-month ... -
Clinical pharmacokinetic drug interactions associated with artemisinin derivatives and HIV-antivirals
( Springer International Publishing , 2014 , Article Review)Management of HIV and malaria co-infection is challenging due to potential drug-drug interactions between antimalarial and HIV-antiviral drugs. Little is known of the clinical significance of these drug interactions, and ... -
Clinical Pharmacokinetics and Drug Interactions of Doravirine
( Springer-Verlag France , 2018 , Article Review)Doravirine is a new HIV-1 non-nucleoside reverse transcriptase inhibitor that has demonstrated a good efficacy and safety profile in clinical trials. It has a therapeutic profile that makes it an attractive option for ... -
Clinical pharmacokinetics: perceptions of hospital pharmacists in Qatar about how it was taught and how it is applied
( Kluwer Academic Publishers , 2015 , Article)Background The application of clinical pharmacokinetics (PK) is essential when providing pharmaceutical care. Appropriate application of PK monitoring results in improved patient outcomes including decreased mortality, ...