Browsing by Subject "Immune response"

Now showing items 1-7 of 7

    • Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants 

      Hebah A., Al-Khatib; Smatti, Maria K.; Ali, Fatma H.; Zedan, Hadeel T.; Thomas, Swapna; ... more authors ( Elsevier , 2022 , Article)
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ...

    • Genome-wide association study identifies several loci for HEV seropositivity 

      Maria K., Smatti; Al-Sarraj, Yasser A.; Albagha, Omar; Yassine, Hadi M. ( Elsevier , 2023 , Article)
      Hepatitis E viral (HEV) infection imposes a heavy global health burden. The variability in the prevalence of serological markers of HEV infection between different ethnic groups proposes a host genetic influence. Here, we ...

    • Immunomodulatory effects of vitamin d supplementation in a deficient population 

      Garand, Mathieu; Toufiq, Mohammed; Singh, Parul; Huang, Susie Shih Yin; Tomei, Sara; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)
      In addition to its canonical functions, vitamin D has been proposed to be an important mediator of the immune system. Despite ample sunshine, vitamin D deficiency is prevalent (>80%) in the Middle East, resulting in a high ...

    • Impact of physical exercise on gut microbiome, inflammation, and the pathobiology of metabolic disorders 

      Sohail, Muhammad U.; Yassine, Hadi M.; Sohail, Aaqib; Al Thani, Asmaa A. ( Society for Biomedical Diabetes Research , 2019 , Article)
      BACKGROUND: The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and ...

    • Microneedles: A new generation vaccine delivery system 

      Menon, Ipshita; Bagwe, Priyal; Gomes, Keegan Braz; Bajaj, Lotika; Gala, Rikhav; ... more authors ( MDPI , 2021 , Article Review)
      Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated. ...

    • The Role of Surface Chemistry in the Osseointegration of PEEK Implants 

      Buck E.; Lee S.; Gao Q.; Tran S.D.; Tamimi F.; ... more authors ( American Chemical Society , 2022 , Article)
      Poly(etheretherketone) (PEEK) implants suffer from poor osseointegration because of chronic inflammation. In this study, we hypothesized that adding NH2and COOH groups to the surface of PEEK could modulate macrophage ...

    • Viral-Induced Enhanced Disease Illness 

      Smatti, Maria K; Al Thani, Asmaa A; Yassine, Hadi M ( Frontiers Media , 2018 , Article)
      Understanding immune responses to viral infections is crucial to progress in the quest for effective infection prevention and control. The host immunity involves various mechanisms to combat viral infections. Under certain ...