Browsing by Subject "cytotoxicity"
Now showing items 1-14 of 14
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An Adjuvanted Inactivated SARS-CoV-2 Microparticulate Vaccine Delivered Using Microneedles Induces a Robust Immune Response in Vaccinated Mice
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)SARS-CoV-2, the causal agent of COVID-19, is a contagious respiratory virus that frequently mutates, giving rise to variant strains and leading to reduced vaccine efficacy against the variants. Frequent vaccination against ... -
Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa
( Taylor & Francis , 2017 , Article)Over the past two decades, studies have documented the wide-range anti-cancer effects of Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active ingredient, has also been extensively studied ... -
Application of copper nanoparticles containing natural compounds in the treatment of bacterial and fungal diseases
( Wiley , 2020 , Article)© 2020 John Wiley & Sons, Ltd. The development of nanotechnology has generated different nanoscale-sized materials, with metal-based nanomaterials being some of the most interesting and promising. Thousands of articles ... -
Characterization and anti-acute T cell leukemia properties of silver nanoparticles synthesized by a green approach for bioremediation applications: Introducing a new chemotherapeutic drug for clinical trial studies
( Wiley , 2020 , Article)© 2020 John Wiley & Sons, Ltd. In recent years, biosynthesis of silver nanoparticles using plant extracts and bioactive compounds has gained much attention. Green synthesis of nanoparticles is eco-friendly, cost-effective, ... -
Characterization and ex vivo evaluation of curcumin nanoethosomes for melanoma treatment
( Taylor & Francis , 2022 , Article)This study aimed at developing curcumin nanoethosomes (Cur-Ets) with superior skin permeation intended for melanoma treatment. Although curcumin is active against many types of skin cancers, a suitable topical formulation ... -
Ethanol-based proliposome delivery systems of paclitaxel for in vitro application against brain cancer cells
( Taylor and Francis Ltd , 2018 , Article)In this study the anticancer activity of paclitaxel-loaded nano-liposomes on glioma cell lines was investigated. Soya phosphatidylcholine:cholesterol (SPC:Chol), hydrogenated soya phosphatidylcholine:cholesterol (HSPC:Chol) ... -
Evaluation of the Cytotoxic Behavior of Fungal Extracellular Synthesized Ag Nanoparticles Using Confocal Laser Scanning Microscope
( MDPI AG , 2016 , Article)Silver nanoparticles have been synthesized by subjecting a reaction medium to a Fusarium oxysporum biomass at 28 °C for 96 h. The biosynthesized Ag nanoparticles were characterized on the basis of their anticipated peak ... -
Evaluation of the Influence of Eggshell (ES) Concentration on the Degradation Behavior of Mg–2.5Zn Biodegradable Alloy in Simulated Body Fluid
( American Chemical Society (ACS) , 2023 , Article)Currently, permanent vascular stents are fabricated using titanium and stainless steel implants that are nondegradable and offer high stability, but they have certain disadvantages. For example, the prolonged exposition ... -
Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin.
( MDPI , 2020 , Article)The approach of drug delivery systems emphasizes the use of nanoparticles as a vehicle, offering the optional property of delivering drugs as a single dose rather than in multiple doses. The current study aims to improve ... -
JC-10 probe as a novel method for analyzing the mitochondrial membrane potential and cell stress in whole zebrafish embryos
( Oxford University Press , 2021 , Article)Background: A sensitive method to investigate cellular stress and cytotoxicity is based on measuring mitochondrial membrane potential. Recently, JC-10, was developed to measure mitochondrial membrane potential in vitro and ... -
Phytochemical-assisted biosynthesis of silver nanoparticles from Ajuga bracteosa for biomedical applications
( Institute of Physics Publishing , 2020 , Article)Silver nanoparticles (AgNPs) synthesized from plant extracts are widely used for the cure of many diseases from fever to cancers. Keeping in view the medicinal value of AgNPs, here we report a cost-effective phytochemical ... -
Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production
( Elsevier , 2021 , Book chapter)RKIP (Raf kinase inhibitory protein) is a metastatic suppressor and a chemo-immuno-sensitizer. The deficiency or loss of RKIP has been linked with different cancer types, resulting in the activation of the MAPK pathway, ... -
Stem cells based in vitro models: Trends and prospects in biomaterials cytotoxicity studies
( IOP Publishing Ltd , 2021 , Article)Advanced biomaterials are increasingly used for numerous medical applications from the delivery of cancer-targeted therapeutics to the treatment of cardiovascular diseases. The issues of foreign body reactions induced by ... -
Urine as a Main Effector in Urological Tissue Engineering—A Double-Edged Sword
(2020 , Article)In order to reconstruct injured urinary tract tissues, biodegradable scaffolds with autologous seeded cells are explored in this work. However, when cells are obtained via biopsy from individuals who have damaged organs ...