Browsing by Subject "Colorectal cancer"
Now showing items 1-20 of 23
-
2-Nucleobase-substituted 4,6-Diaminotriazine Analogs: Synthesis and Anti-cancer Activity in 5-Fluorouracil-Sensitive and Resistant Colorectal Cancer Cells.
( Bentham Science Publishers , 2022 , Article)Cancer continues to be the second leading cause of death worldwide with colorectal cancer (CRC) being the third most common type. Despite significant advances in cancer therapies, current treatment of CRC remains suboptimal. ... -
Association of genetic variants with colorectal cancer in the extended MENA region: A systematic review
( Bentham Science Publishers , 2019 , Article)Colorectal cancer (CRC) is the third most common cancer worldwide and the third leading cause of cancer-related death. It is a heterogeneous disease that develops through different genetic and epigenetic mechanisms. To ... -
Automatic classification of colorectal and prostatic histologic tumor images using multiscale multispectral local binary pattern texture features and stacked generalization
( Elsevier B.V. , 2018 , Article)This paper proposes a new multispectral multiscale local binary pattern feature extraction method for automatic classification of colorectal and prostatic tumor biopsies samples. A multilevel stacked generalization ... -
Cadmium induces migration of colon cancer cells: Roles of reactive oxygen species, p38 and cyclooxygenase-2
( Cell Physiol Biochem Press GmbH & Co KG , 2019 , Article)Background/Aims: Cadmium (Cd) is a heavy metal contaminant whose toxicity is associated with colorectal cancer (CRC). However, the underlying molecular mechanisms of Cd-induced CRC malignancy remain obscure. Methods: A ... -
Cetuximab-conjugated chitosan-pectinate (modified) composite nanoparticles for targeting colon cancer
( Elsevier B.V. , 2019 , Article)In the present study, we successfully developed a cetuximab-conjugated modified citrus pectin-chitosan nanoparticles for targeted delivery of curcumin (Cet-MCPCNPs) for the treatment of colorectal cancer. In vitro analyses ... -
A Chromosome 9p24.1 Amplification in Colorectal Cancer with Metastases to the Kidney and Adrenal Gland: A Case Report
( karger , 2023 , Article)Colorectal cancer (CRC) is the third leading cause of mortality worldwide. The Food and Drug Administration recently designated pembrolizumab, an immune checkpoint inhibitor (ICI) against a programmed death-1 receptor, as ... -
Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene
( Ivyspring International Publisher , 2014 , Article)Both diabetes and cancer are prevalent diseases whose incidence rates are increasing worldwide, especially in countries that are undergoing rapid industrialization changes. Apparently, lifestyle risk factors including diet, ... -
Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies
( MDPI , 2022 , Article Review)Colorectal cancer (CRC) is the second most deadly cancer. Global incidence and mortality are likely to be increased in the coming decades. Although the deaths associated with CRC are very high in high-income countries, the ... -
Development of injectable PEGylated liposome encapsulating disulfiram for colorectal cancer treatment
( MDPI AG , 2019 , Article)Disulfiram (DS), an anti-alcoholism medicine, shows strong anti-cancer activity in the laboratory, but the application in clinics for anti-cancer therapy has been limited by its prompt metabolism. Conventional liposomes ... -
Dietary patterns and colorectal cancer
( Elsevier , 2016 , Article)Summary Background & aimsDietary pattern and lifestyle have been reported to be important risk factors in the development of colorectal cancer (CRC). However, the mechanism of action of dietary factors in CRC disease is ... -
Elaeagnus Angustifolia extract inhabits cell invasion of human colorectal cancer cells and increases the survival rate of the Drosophila colon cancer model
( Qatar University Press , 2021 , Poster)Colorectal cancer (CRC), the third most common type of cancer in the world, is an aggressive type of cancer with high tendency to metastasize and invade to other tissues and distant organs. Traditional CRC treatment regimen ... -
Epstein-Barr virus (EBV) status in colorectal cancer: a mini review
( Taylor & Francis , 2018 , Article)Epstein-Barr virus (EBV) is a well-characterized oncovirus, associated with several malignancies. The complex and heterogeneous nature of colorectal cancer (CRC) has led to many epidemiological causal associations with ... -
Fast Foods, Sweets and Beverage Consumption and Risk of Colorectal Cancer: A Case-Control Study in Jordan
( West Asia Organization for Cancer Prevention , 2018 , Article)Background: The effects of consuming fast foods, sweets and beverages on the development of colorectal cancer (CRC) are unclear. The aim of this case-control study was to assess possible associations between the consumption ... -
Glandular structure-guided classification of microscopic colorectal images using deep learning
( Elsevier Ltd , 2019 , Article)In this work, we propose to automate the pre-cancerous tissue abnormality analysis by performing the classification of image patches using a novel two-stage convolutional neural network (CNN) based framework. Rather than ... -
Identification of potential circadian genes and associated pathways in colorectal cancer progression and prognosis using microarray gene expression analysis
( Elsevier , 2023 , Book chapter)Colorectal cancer (CRC) is third cancer causing death in the world. CRC is associated with disrupting the circadian rhythm (CR), closely associating the CRC progression and the dysregulation of genes involved in the ... -
Incidence and association of high-risk HPVs and EBV in patients with advanced stages of colorectal cancer from Qatar
( Taylor and Francis Ltd. , 2023 , Article)High-risk Human Papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are present and involved in several types of human carcinomas, including cervical and, head and neck cancers. Nevertheless, their presence and association ... -
Molecular characterization of circadian gene expression and its correlation with survival percentage in colorectal cancer patients
( Elsevier , 2023 , Book chapter)Colorectal cancer (CRC) is a form of cancer characterized by many symptoms and readily metastasizes to different organs in the body. Circadian rhythm is one of the many processes that is observed to be dysregulated in ... -
Nanoparticles: Attractive tools to treat colorectal cancer
( Elsevier , 2022 , Article)Colorectal Cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Despite the notable advances achieved over the last few decades, CRC remains a hard-to-treat deadly disease in many patients. This ... -
Protein expression profiling identifies key proteins and pathways involved in growth inhibitory effects exerted by guggulsterone in human colorectal cancer cells
( MDPI AG , 2019 , Article)Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such ... -
Snornas and mirnas networks underlying covid-19 disease severity
( MDPI , 2021 , Article)There is a lack of predictive markers for early and rapid identification of disease progression in COVID-19 patients. Our study aims at identifying microRNAs (miRNAs)/small nucleolar RNAs (snoRNAs) as potential biomarkers ...