Browsing by Subject "diabetic retinopathy"
Now showing items 1-5 of 5
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Adiponectin Ameliorates Hyperglycemia-Induced Retinal Endothelial Dysfunction, Highlighting Pathways, Regulators, and Networks
( dovepress , 2022 , Article)Background: The pathophysiology of diabetic retinopathy (DR) is multifaced. A low level of circulating adiponectin (APN) in type 2 diabetes is associated with microvasculature complications, and its role in the evolution ... -
Diabetic Reinopathy Classification using Deep Learning
(2020 , Master Thesis)With diabetes growing at an alarming rate, changes in the retina of diabetic patients causes a condition called diabetic retinopathy which eventually leads to blindness. Early detection of diabetic retinopathy is the best ... -
EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
(2016 , Master Thesis)Background: Diabetic Retinopathy (DR) is an inflammatory disease mainly characterized by the dysfunction of the retinal blood vessels. Several studies reported a possible link between the hyperglycemia and the activation ... -
The Expression of Retinal miRNA Evoked by Hyperglycemia and After Adiponectin Treatment in Human Retinal Endothelial Cells
(2018 , Master Thesis)Background: Diabetes mellitus is a chronic metabolic disease resulting in microvascular complications including diabetic retinopathy (DR). Adiponectin (ApN) is an adipokine hormone, and recent studies demonstrated that ApN ... -
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
( American Society for Biochemistry and Molecular Biology , 2015 , Article)Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived ...