Hepatitis-B Markers In Sera Of Egyptian Hepatoma Patients

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Hepatitis-B Markers In Sera Of Egyptian Hepatoma Patients

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dc.contributor.author El Asser, A. A. [عبد الباسط الاعصر] en_US
dc.date.accessioned 2009-11-25T15:30:46Z
dc.date.available 2009-11-25T15:30:46Z
dc.date.issued 1994 en_US
dc.identifier.citation Qatar University Science Journal, 1994, Vol. 14, No. خاص, Pages 21-25. en_US
dc.identifier.uri http://hdl.handle.net/10576/10231
dc.description.abstract The present study was performed on 52 hepatoma patients; 46 of them were of the histopathological type known as hepatic cell carcinoma (HCC), aiming to investigate the possible role of hepatitis B viral (HBV) infection in the etiology of hepatoma; among Egyptians, with special reference to hepatocellular carcinoma. To fulfill this aim, the three hepatitis B markers namely hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (HBsAb) and hepatitis B core antibody (HBcAb) were estimated in sera of patients and healthy controls. The present study revealed a striking correlation between clinical or subclinical history of HBV infection or even carrier rate, and hepatoma, since 94.2% of the hepatoma patients were positive for one or more of the hepatitis markers studied. The higher prevalence of HBV infection was observed among HCC patients (97%) than among other types of hepatoma patients (66%, P = 0.03). HBsAb and HBcAb were positive among 80.8% (P<0.01) and 84.6% (P<0.01) of hepatoma patients ; respectively, whereas they were completely absent in sera of controls. On the other hand HBsAg was positive among 13.5% only of the hepatoma patients, revealing no significant changes when compared to controls (P = 0.133). Nevertheless, no significant correlation was observed between HBsAb positive patients and those who were positive for HBcAb (P = 0.35). en_US
dc.description.abstract شمل هذا البحث 52 مرضياً مصابون بسرطان الكبد، من بينهم 46 مريض مصابون . ar
dc.language.iso en en_US
dc.publisher Qatar University en_US
dc.subject Biochemistry en_US
dc.subject الكيمياء الحيوية ar
dc.title Hepatitis-B Markers In Sera Of Egyptian Hepatoma Patients en_US
dc.title.alternative دلالات الالتهاب الكبدى الوبائي (ب) في مصل مرضي سرطان الكبد المصرين ar
dc.type Article en_US
dc.identifier.pagination 21-25 en_US
dc.identifier.issue خاص en_US
dc.identifier.volume 14 en_US

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