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Author Al-Obaidli, Aishaen_US
Author Sabbagh, Audreyen_US
Author Pravin, Sahayaen_US
Author Krishnamoorthy, Rajagopolen_US
Available date 2009-12-29T07:09:14Zen_US
Publication Date 2008-12-20en_US
Publication Name Forensic Science International: Genetics
Citation Al-Obaidli, A., Sabbagh, A., Pravin, S., & Krishnamoorthy, R. (2009). Present day inbreeding does not forbid the forensic utility of commonly explored STR loci: A case study of native Qataris. Forensic Science International: Genetics, 4(1), e11–e13en_US
URI http://dx.doi.org/10.1016/j.fsigen.2008.12.005en_US
URI http://hdl.handle.net/10576/10555en_US
Abstract Allele frequency distribution of 15 short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, and FGA) was studied in a sample of 120 unrelated native Qatari population using the AmpFISTR® Identifiler kit (Applied Biosystems, Foster city, CA, USA). All loci met Hardy-Weinberg expectations and there was no evidence for linkage disequilibrium between any of the marker pairs. The most discriminating locus was D2S1338 with a power of discrimination (PD) of 0.969, while the lowest one was TPOX, yet with a PD of 0.821. For all the 15 loci, the combined PD and the combined power of exclusion (PE) were respectively 0.99999999 and 0.99999744. Thus the probability of finding two individuals bearing an identical 15 locus DNA profile is one in 108 native Qatari subjects and this surpasses largely the present day Qatari natives consisting of around 3.5 × 105 individuals. The results of this study demonstrate the usefulness and reliability of the AmpFISTR® Identifiler kit for individual identification in forensic studies in the native Qatari population, despite the current practice of high inbreeding.en_US
Language enen_US
Publisher Elsevier Ireland Ltd.en_US
Subject Forensicen_US
Subject Inbreedingen_US
Subject Populationen_US
Subject Qataren_US
Subject STRen_US
Title Present day inbreeding does not forbid the forensic utility of commonly explored STR loci: A case study of native Qatarisen_US
Type Articleen_US


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