The authors reply

Abstract

Among this large variety of ICU patients, some groups are inherently of high risk for PI development, such as burn- injured, obese, and patients with peripheral vascular disease. By lacking specific data, the authors were unable to perform subanalyses quantifying occurrence rates among ICU high-risk groups, whereas this information could have assisted clinicians in determining the extent and nature of preventive strategies for these patients. It was also identified that cumulative incidence studies of the general hospital population are limited, leaving a gap of knowledge in determining which Pls are present upon ICU admission and which ones are ICU-acquired. This could be of value in identifying and addressing crosscutting challenges at hospital level, and in guiding treatment and prevention strategies that potentially help alleviating the burden of PI in the ICU.