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Comparison of potential inhibitors and targeting fat mass and obesity-associated protein causing diabesity through docking and molecular dynamics strategies.
(
Wiley
, 2021 , Article)
Genome-wide association studies (GWAS) have identified an association between polymorphisms in the FTO gene and obesity. The FTO: rs9939609, an intronic variant, is considered a risk allele for developing diabesity in ...
miR-21 mimic blocks obesity in mice: A novel therapeutic option
(
Elsevier
, 2021 , Article)
MicroRNAs (miRNAs) are promising drug targets for obesity and metabolic disorders. Recently, miRNA mimics are providing a unique mechanism of action that guides the process for drug development and sets out the context of ...
Identification of Adolescents with Adiposities and Elevated Blood Pressure and Implementation of Preventive Measures Warrants the Use of Multiple Clinical Assessment Tools
(
MDPI
, 2021 , Article)
Background: The burden of abdominal adiposity has increased globally, which is recognized as a key condition for the development of obesity-related disorders among youth, including type 2 diabetes, cardiovascular disease, ...
Consequences of a Great Crisis on Chronic Diseases: How Childhood Exposures May Shape Future Health
(
John Wiley and Sons Inc
, 2021 , Article)
[No abstract available]
Trends and socioeconomic factors associated with overweight/obesity among three reproductive age groups of women in Nepal
(
Wiley
, 2021 , Article)
Introduction: Overweight/obesity represents a major and increasing burden in Nepal where women in reproductive-aged groups are highly affected. We aimed to explore the trends and association of overweight by socioeconomic ...
Effect of Adipose derived mesenchymal stem cells on multiple Organ Injuries in diet-induced obese mice
(
Taylor and Francis Ltd.
, 2021 , Article)
Background: Obesity is a complex disease involving the accumulation of body fat that can inflict a substantial risk to health due to the potent role it plays in the development of a series of chronic diseases including ...
Environmental Factors, Lifestyle Risk Factors, and Host Characteristics Associated With Philadelphia Negative Myeloproliferative Neoplasm: A Systematic Review
(
SAGE Publications Ltd
, 2021 , Article Review)
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by the overproduction of mature myeloid cells and are often associated with an acquired genetic mutation of Janus Kinase2V617F. ...
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
(
eLife Sciences Publications
, 2021 , Article)
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated ...