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The role of gene gjb2 and connexin 26 in hearing impairment
(
Palladin Institute of Biochemistry of the NASU
, 2018 , Article Review)
Gap Junction Beta 2 (GJB2) gene mutations are the leading causes of hereditary hearing impairment. This gene encodes various gap junction proteins such as connexin 26 (Cx26), which facilitate K+ homeostasis inside the ...
Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy
(
Taylor and Francis Ltd
, 2018 , Article Review)
Introduction: Exploration in the field of epigenetics has revealed the diverse roles of the protein arginine methyltransferase (PRMT) family of proteins in multiple disease states. These findings have led to the development ...
Direct cardiovascular impact of SGLT2 inhibitors: mechanisms and effects
(
Springer New York LLC
, 2018 , Article Review)
Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors ...
Towards understanding the mechanisms of actions of carcinoembryonic antigen-related cell adhesion molecule 6 in cancer progression
(
Wiley Open Access
, 2017 , Article Review)
Human carcinoembryonic antigen (CEA) is the prototypic member of a family of
highly related cell surface glycoproteins that includes carcinoembryonic antigenrelated
cell adhesion molecule 6 (CEACAM6) and others. CEACAM6 ...
Novel CD44-downstream signaling pathways mediating breast tumor invasion
(
Ivyspring International Publisher
, 2018 , Article Review)
CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell
and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways,
including ...
Variation in plant litter decomposition rates across extreme dry environments in Qatar
(
University of Akron
, 2017 , Article Review)
Decomposition of plant litter is a key process for transfer of carbon and nutrients in ecosystems. Carbon contained in decaying biomass is released to the atmosphere as respired CO2, a greenhouse gas that contributes to ...
New records of freshwater crustaceans from vernal pools of Qatar including large branchiopods and a Mysid Shrimp, a natural resource of economic importance for the aquaculture industry
(
University of Akron
, 2017 , Article Review)
During an intensive survey of fresh water macroinvertebrates from vernal and permanent inland waters of Qatar, at the wet seasons of 2016 and 2017, seven species of crustaceans (one cladoceran, one notostaracan, two ...
Towards understanding the genetics of Autism
(
Frontiers in Bioscience
, 2016 , Article Review)
Autism spectrum disorder (ASD) includes a group of neurodevelopmental disorders that affect communication skills, social interaction and intellectual ability. Despite evidence suggesting a strong genetic link with ASD, the ...
Conventional and Upcoming Sulfur-Cleaning Technologies for Petroleum Fuel: A Review
(
Wiley-VCH Verlag
, 2016 , Article Review)
Environmental regulations on the quality of liquid fuels continue to create more requirements to produce a near-to-zero sulfur content. The hydrodesulfurization process has a high running cost and suffers from incomplete ...
Energy efficiency of direct contact membrane distillation
(
Elsevier B.V.
, 2018 , Article Review)
Membrane distillation (MD) is a promising technology due to its ability to function using low temperature differences and low-quality heat sources, thus allowing it to operate on solar or waste heat. The flux and energy ...