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Author Klukova, L.
Author Bertok, T.
Author Kasak, P.
Author Tkac, J.
Available date 2016-02-28T12:50:46Z
Publication Date 2014
Publication Name Analytical Methods
Citation Klukova, L., Bertok, T., Kasak, P., Tkac, J., "Nanoscale-controlled architecture for the development of ultrasensitive lectin biosensors applicable in glycomics", (2014) Analytical Methods, 6 (14), pp. 4922-4931.
ISSN 1759-9660
URI http://dx.doi.org/10.1039/c4ay00495g
URI http://hdl.handle.net/10576/4185
Abstract In this mini-review the most advanced patterning protocols and transducing schemes for the development of ultrasensitive label-free and label-based lectin biosensors for the glycoprofiling of disease markers and some cancerous cells are described. The performance of such lectin biosensors with interfacial properties tuned to the nanoscale are critically compared to the most sensitive immunoassay format of analysis, and challenges for the future are discussed. In addition the key elements for further development of these devices are considered, with a view to improvement of their robustness and practical applicability.
Sponsor APVV 0282-11 and VEGA 2/0162/14 provided by the Slovak grant agencies. European Research Council (ERC Grant Agreement No. 311532) and from the European Union Seventh Framework Program (FP/2007�2013 with Grant Agreement No. 317420). NPRP grant 6-381-1-078 from the Qatar National Research Fund (a member of the Qatar Foundation).
Language en
Publisher Royal Society of Chemistry
Subject Bioassay
Subject Nanotechnology
Subject Proteins
Subject Cancerous cells
Subject Disease markers
Subject Interfacial property
Subject Key elements
Subject Label free
Subject Nano scale
Subject Transducing
Subject Ultra sensitives
Title Nanoscale-controlled architecture for the development of ultrasensitive lectin biosensors applicable in glycomics
Type Article
Pagination 4922-4931
Issue Number 14
Volume Number 6


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