Browsing College of Medicine by Title
Now showing items 351-370 of 1344
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Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET.
( Humana Press, New York, NY , 2019 , Book chapter)Ubiquitination of G protein-coupled receptors (GPCRs) is an important dynamic posttranslational modification that has been linked to the intracellular trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs ... -
Determinants of Atrial Fibrillation Development among Patients undergoing Ibrutinib Therapy
( Marshfield Clinic , 2022 , Article)Objective: Within the last decade, the use of ibrutinib, a first-generation, non-selective, irreversible Burton's tyrosine kinase inhibitor for the treatment of hematological malignancies has proven highly effective in ... -
The determination of causality of drug induced liver injury in patients with COVID-19 clinical syndrome
( Public Library of Science , 2022 , Article)Background Drug induced liver injury (DILI) is a rising morbidity amongst patients with COVID-19 clinical syndrome. The updated RUCAM causality assessment scale is validated for use in the general population, but its utility ... -
Determination of Medicago orbicularis Antioxidant, Antihemolytic, and Anti-Cancerous Activities and Its Augmentation of Cisplatin-Induced Cytotoxicity in A549 Lung Cancer Cells
( MDPI , 2023 , Article)The anti-lung cancer properties of the plant Medicago orbicularis have not been explored yet. Therefore, we identified its phytochemical composition and investigated the antioxidant, anti-hemolytic, and anti-cancerous ... -
Determining the conclusiveness of a meta-analysis.
( Wolters Kluwer Health , 2024 , Article)The pursuit of conclusive evidence related to an unanswered foreground (decision-making) question has been the driving factor behind multiple ongoing and planned randomized controlled trials as well as meta-analyses. ... -
Developing a gender sensitive women's mental health service in Qatar: A rewarding challenge
( Elsevier , 2022 , Article)Investigations into gender differences in the epidemiology of common mental disorders have highlighted the fundamental role of socio-economic factors as the key determinants in experiencing mental ill health and access to ... -
Development and diagnostic validation of the Brisbane Evidence-Based Language Test.
( Taylor & Francis , 2020 , Article)To describe the development and determine the diagnostic accuracy of the Brisbane Evidence-Based Language Test in detecting aphasia. Consecutive acute stroke admissions ( = 100; mean = 66.49y) participated in a single ... -
Development and initial validation of stigma towards healthcare providers working with covid-19 patients scale (S19-hcps)
( Dove Medical Press Ltd , 2021 , Article)Purpose: The S19-HCPs tool evaluates the stigma towards healthcare providers working with patients with COVID-19. Materials and Methods: The psychometric properties of the Arabic and English versions of the S19-HCPs were ... -
Development and Validation of an Early Scoring System for Prediction of Disease Severity in COVID-19 Using Complete Blood Count Parameters
( Institute of Electrical and Electronics Engineers Inc. , 2021 , Article)The coronavirus disease 2019 (COVID-19) after outbreaking in Wuhan increasingly spread throughout the world. Fast, reliable, and easily accessible clinical assessment of the severity of the disease can help in allocating ... -
Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs
( Elsevier , 2017 , Article)PurposeThere are no published instruments, which measure tutor motivation for conducting small group tutorials in problem-based learning programs. Therefore, we aimed to develop a motivation for tutoring questionnaire in ... -
Development of an evidence-based model for predicting patient, provider, and appointment factors that influence no-shows in a rural healthcare system
(2023 , Article)Background: No-show appointments pose a significant challenge for healthcare providers, particularly in rural areas. In this study, we developed an evidence-based predictive model for patient no-shows at the Marshfield ... -
Development of an in-house COVID-19 serology ELISA Test
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Background: COVID-19 pandemic created an unprecedented demand for reagents and diagnostic tools to confirm COVID-19 cases. Thus, the development of a robust in-house diagnostic test is considered of high importance. Within ... -
Development of discriminant functions to estimate sex in upper limb bones for mixed ancestry South Africans
( Elsevier , 2019 , Article)The Chartered Society of Forensic Sciences South Africa has one of the highest murder rates in the world, which is associated with an increasing number of unidentified individuals. Forensic anthropologists can assist in ... -
Development of mental health services for lower-skilled migrant workers in Qatar
( Elsevier , 2021 , Article)The largest group of migrants in Gulf Cooperation Council (GCC) countries are lower-skilled migrant workers. GCC countries have witnessed significant healthcare infrastructure investments over recent decades. Despite this, ... -
Development of Novel Chalcone Analogs as Potential Multi-Targeted Therapies for Castration-Resistant Prostate Cancer
( Qatar University Press , 2021 , Poster)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ... -
Development of oral cancer: Risk factors and prevention strategies
( Springer International Publishing , 2017 , Book)This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. ... -
Development of Recombinant PLC-Zeta Protein as a Therapeutic Intervention for the Clinical Treatment of Oocyte Activation Failure
( MDPI , 2024 , Article)The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca2+ release responsible for oocyte activation during mammalian fertilization. The ... -
Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model
( American Chemical Society , 2022 , Article)Background: nanotechnology is one of the fastest-growing areas, and it is expected to have a substantial economic and social impact in the upcoming years. Gold particles (AuNPs) offer an opportunity for wide-ranging ... -
Dexamethasone induces the expression and function of tryptophan-2-3-dioxygenase in sk-mel-28 melanoma cells
( MDPI , 2021 , Article)Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed ...