Browsing College of Medicine by Title
Now showing items 613-632 of 1337
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High-risk human papillomaviruses and epstein-barr virus presence and crosstalk in human oral carcinogenesis
( Springer International Publishing , 2017 , Book chapter)Oral cancer is the most frequent type of malignancy of the head and neck area worldwide. This cancer is a major cause of mortality in several parts of the world especially in certain Asian countries. In fact, the majority ... -
High-risk human papillomaviruses and epstein–barr virus in colorectal cancer and their association with clinicopathological status
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Colorectal cancer (CRC) is a common malignancy with a high mortality rate worldwide. It is a complex, multifactorial disease that is strongly impacted by both hereditary and environmental factors. The role of microbes ... -
High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder
( Frontiers Media SA , 2023 , Article)Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by defects in two core domains, social/communication skills and restricted/repetitive behaviors or interests. There is no approved ... -
Higher serum uric acid is associated with poorer cognitive performance in healthy middle-aged people: a cross-sectional study
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Age-related cognitive impairment can occur many years before the onset of the clinical symptoms of dementia. Uric acid (UA), a metabolite of purine-rich foods, has been shown to be positively associated with improved ... -
Highly Sensitive Detection and Differentiation of Endotoxins Derived from Bacterial Pathogens by Surface-Enhanced Raman Scattering.
( MDPI , 2021 , Article)Bacterial endotoxins, as major components of Gram-negative bacterial outer membrane leaflets and a well-characterized TLR4-MD-2 ligand, are lipopolysaccharides (LPSs) that are constantly shed from bacteria during growth ... -
High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines
( American Association for the Advancement of Science , 2022 , Article)Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ... -
Histological evaluation of the male rabbit urethra: Regional and age-related variations and their relevance in tissue engineering and reconstructive surgery applications
( Sidra Medicine , 2019 , Conference Paper)Background data: The male rabbit is the most frequently utilized animal model for urethral preclinical experiments. Surprisingly, little is known about the regional variations in the tissue along the urethra, or how age ... -
Home Cancer Care Research: A Bibliometric and Visualization Analysis (1990–2021)
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Home cancer care research (HCCR) has accelerated, as considerable attention has been placed on reducing cancer-related health costs and enhancing cancer patients’ quality of life. Understanding the current status of HCCR ... -
Homozygous mutation in MCM7 causes autosomal recessive primary microcephaly and intellectual disability
( BMJ Publishing Group , 2021 , Article)Minichromosomal maintenance (MCM) complex components 2, 4, 5 and 6 have been linked to human disease with phenotypes including microcephaly and intellectual disability. The MCM complex has DNA helicase activity and is ... -
Hormones in experimental autoimmune encephalomyelitis (EAE) animal models
( De Gruyter , 2021 , Article)Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) in which activated immune cells attack the CNS and cause inflammation and demyelination. While the etiology of MS is still ... -
House dust mite-treated PAR2 over-expressor mouse: A novel model of atopic dermatitis
( Blackwell Publishing Ltd , 2019 , Article)Background Atopic dermatitis (AD) is a complex skin disease involving causative effects from both intrinsic and extrinsic sources. Murine models of the disease often fall short in one of these components and, as a result, ... -
How can we improve the measurement of receptor signaling bias?
( Taylor & Francis Group , 2023 , Article)G protein-coupled receptors (GPCRs) are flexible and dynamic signaling entities that can adopt multiple active conformations upon activation [Citation1,Citation2]. However, each agonist stabilizes a distinct receptor ... -
How do tobacco control policies work in low-income and middle-income countries? A realist synthesis
( BMJ , 2022 , Article)Background The burden of tobacco use is disproportionately high in low- and middle-income countries (LMICs). There is scarce theorisation on what works with respect to implementation of tobacco control policies in these ... -
How to deal with rare pediatric surgical diseases in the small developing country with limited resources: Insights from Bosnia and Herzegovina
( Elsevier , 2022 , Other)The European Union Regulation on Orphan Medicinal Products defines a disease/condition as rare if it affects < 1 in 2.000 in the European population, making the prevalence data a key tool in creating health care policies ... -
HPV and Recurrent Respiratory Papillomatosis: A Brief Review
( MDPI , 2021 , Article)Recurrent Respiratory Papillomatosis (RRP) is a rare but severe manifestation of human papillomavirus (HPV). As our knowledge about HPV infections has expanded, it has become possible to understand the course of RRP disease ... -
Human antigen R: Exploring its inflammatory response impact and significance in cardiometabolic disorders
( Wiley , 2024 , Article Review)RNA-binding proteins (RBPs) play a crucial role in the regulation of posttranscriptional RNA networks, which can undergo dysregulation in many pathological conditions. Human antigen R (HuR) is a highly researched RBP that ... -
Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers.
( Public Library of Science , 2020 , Article)Octamer binding transcription factor-4 (Oct4), is highly expressed in stem cells and has indispensable roles in pluripotency and cellular reprogramming. In contrast to other factors used for cellular reprogramming, a role ... -
Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.
( MDPI , 2020 , Article)Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, ... -
Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
( MDPI , 2022 , Article Review)The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ... -
Human rights as the key driver for development of Learning Disability services in Qatar
( Elsevier , 2023 , Article)Growing international consensus in recognising rights of individuals with disability to enabling environments has spurred on provision of services for support for these individuals. The provision of this support has however ...