Browsing Biomedical Research Center Research by Author "Georgakopoulos, Costas"
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Assessment of Serum Cytokines and Oxidative Stress Markers in Elite Athletes Reveals Unique Profiles Associated With Different Sport Disciplines
Sohail, Muhammad U.; Al-Mansoori, Layla; Al-Jaber, Hend; Georgakopoulos, Costas; Donati, Francesco; Botrè, Francesco; Sellami, Maha; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Sohail, Al-Mansoori, Al-Jaber, Georgakopoulos, Donati, Botrè, Sellami and Elrayess. Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This ... -
Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism.
Al-Khelaifi, Fatima; Yousri, Noha A; Diboun, Ilhame; Semenova, Ekaterina A; Kostryukova, Elena S; Kulemin, Nikolay A; Borisov, Oleg V; Andryushchenko, Liliya B; Larin, Andrey K; Generozov, Edward V; Miyamoto-Mikami, Eri; Murakami, Haruka; Zempo, Hirofumi; Miyachi, Motohiko; Takaragawa, Mizuki; Kumagai, Hiroshi; Naito, Hisashi; Fuku, Noriyuki; Abraham, David; Hingorani, Aroon; Donati, Francesco; Botrè, Francesco; Georgakopoulos, Costas; Suhre, Karsten; Ahmetov, Ildus I; Albagha, Omar; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2020 , Article)The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ... -
Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
Athanasiadou, Ioanna; Voss, Sven Christian; El Saftawy, Wesal; Al-Jaber, Hind; Dbes, Najib; Al-Yazedi, Sameera; Samsam, Waseem; Mohamed-Ali, Vidya; Alsayrafi, Mohammed; Valsami, Georgia; Georgakopoulos, Costas... more authors ... less authors ( Human Kinetics Publishers Inc. , 2019 , Article)Low urinary luteinizing hormone (LH) values have been discussed as a marker to detect steroid abuse. However, suppressed LH concentrations related to highly diluted urine samples could be a misleading indication of anabolic ... -
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
Al-Khelaifi, Fatima; Diboun, Ilhame; Donati, Francesco; Botre, Francesco; Abraham, David; Hingorani, Aroon; Albagha, Omar; Georgakopoulos, Costas; Suhre, Karsten; Yousri, Noha A... more authors ... less authors ( Nature Research , 2019 , Article)Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ... -
Metabolic profiling of elite athletes with different cardiovascular demand
Al-Khelaifi, Fatima; Donati, Francesco; Botrè, Francesco; Latiff, Aishah; Abraham, David; Hingorani, Aroon; Georgakopoulos, Costas; Suhre, Karsten; Yousri, Noha A; Elrayess, Mohamed A... more authors ... less authors ( John Wiley & Sons Ltd , 2019 , Article)Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ... -
Metabolomics and doping analysis: promises and pitfalls.
Botrè, Francesco; Georgakopoulos, Costas; Elrayess, Mohamed A ( Future Science , 2020 , Article)This brief commentary presents an overview of the potential utility of metabolomics-based approaches in doping analysis, with particular emphasis on areas where the current analytical procedures would most benefit from ...