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1 [4 (methylsulfonyl)phenyl] 3 (2,4,6 trimethoxyphenyl)prop 2 en 1 one; 1 [4 (methylthio)phenyl] 3 (2,4,6 trimethoxyphenyl)prop 2 en 1 one; 1 [4 (methylthio)phenyl] 3 [3 (trifluoromethyl)phenyl]prop 2 en 1 one; 3 (2 methoxyphenyl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one; 3 (2,5 dimethoxyphenyl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one; 3 (6 bromobenzo[d][1,3]dioxol 5 yl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one; 3 (6 bromobenzo[d][1,3]dioxol 5 yl) 1 [4 (methylthio)phenyl]prop 2 en 1 one; 3 (6 bromobenzo[d][1,3]dioxol 5 yl) 1 [4 (piperazin 1 yl)phenyl]prop 2 en 1 one; 3 (benzo[b]thiophen 2 yl) 1 (3 methoxyphenyl)prop 2 en 1 one; 3 (benzo[b]thiophen 2 yl) 1 (3,4,5 trimethoxyphenyl)prop 2 en 1 one; 3 (benzo[b]thiophen 2 yl) 1 (benzo[d][1,3]dioxol 5 yl)prop 2 en 1 one; 3 (benzo[b]thiophen 2 yl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one; 3 (benzo[b]thiophen 2 yl) 1 [4 (methylthio)phenyl]prop 2 en 1 one; 3 [2 fluoro 4 (trifluoromethyl)phenyl] 1 [4 (methylthio)phenyl]prop 2 en 1 one; antineoplastic agent; B Raf kinase; beta catenin; chalcone derivative; fascin; paclitaxel; protein Bax; protein bcl 2; unclassified drug; uvomorulin; vimentin; chalcone derivative; KRAS protein, human; protein p21; antiangiogenic activity; antineoplastic activity; apoptosis; Article; BRAF gene; cancer inhibition; cell adhesion; cell cycle; cell viability; colony formation; colorectal cancer; controlled study; down regulation; drug design; drug effect; drug efficacy; drug potency; drug potentiation; drug screening; drug selectivity; drug synthesis; epithelial mesenchymal transition; gene mutation; GI50; HCT 116 cell line; HT-29 cell line; immortalized cell line; in vitro study; in vivo study; LoVo cell line; metastasis; migration inhibition; oncogene K ras; priority journal; proapoptotic activity; process optimization; tumor invasion; tumor suppressor gene; tumor vascularization; upregulation; cell motion; cell proliferation; chemistry; colorectal tumor; genetics; human; tumor cell line; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chalcones; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Humans; Proto-Oncogene Proteins p21(ras) (1)
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