Browsing College of Health Sciences by Title

Now showing items 1522-1541 of 1543

    • Whole-exome sequencing analysis of NSCLC reveals the pathogenic missense variants from cancer-associated genes 

      Kumar S, Udhaya; Balasundaram, Ambritha; Cathryn R, Hephzibah; Varghese, Rinku Polachirakkal; R, Siva; ... more authors ( Elsevier , 2022 , Article)
      Background: Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer. NSCLC accounts for 84% of all lung cancer cases. In recent years, advances in pathway understanding, methods for discovering novel ...

    • A Whole-Genome Sequencing Association Study of Low Bone Mineral Density Identifies New Susceptibility Loci in the Phase I Qatar Biobank Cohort. 

      Younes, Nadin; Syed, Najeeb; Yadav, Santosh K; Haris, Mohammad; Abdallah, Atiyeh M; ... more authors ( MDPI , 2021 , Article)
      Bone density disorders are characterized by a reduction in bone mass density and strength, which lead to an increase in the susceptibility to sudden and unexpected fractures. Despite the serious consequences of low bone ...

    • Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients 

      Al Mana, Hassan; Sundararaju, Sathyavathi; Tsui, Clement K. M.; Perez-Lopez, Andres; Yassine, Hadi; ... more authors ( MDPI , 2021 , Article)
      Antibiotic resistance is a growing public health problem globally, incurring health and cost burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative ...

    • Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension 

      Alsamman, Alsamman M.; Almabrazi, Hakeem; Zayed, Hatem ( MDPI , 2022 , Article)
      Essential hypertension (EH) is a leading risk condition for cardiovascular and renal com-plications. While multiple genes are associated with EH, little is known about its genetic etiology. Therefore, this study aimed to ...

    • Why do tendon researchers overlook the patient's psychological state? The review with no papers. 

      Mc Auliffe, Seán; O'Sullivan, Kieran; Whiteley, Rod; Korakakis, Vasileios ( BMJ Publishing Group , 2020 , Other)
      Exercise or loading interventions remain the conservative treatment of choice in the management of tendinopathy.1 However, as many as 60% of individuals experience continued symptoms, while up to a quarter of patients ...

    • Why does the adverse effect of inappropriate MRI for LBP vary by geographic location? An exploratory analysis. 

      Shraim, Mujahed; Cifuentes, Manuel; Willetts, Joanna L; Marucci-Wellman, Helen R; Pransky, Glenn ( BMC , 2019 , Article)
      Early magnetic resonance imaging (eMRI) for nonspecific low back pain (LBP) not adherent to clinical guidelines is linked with prolonged work disability. Although the prevalence of eMRI for occupational LBP varies substantially ...

    • Why rehabilitation must have priority during and after the COVID-19-pandemic: A position statement of the global rehabilitation alliance 

      Gutenbrunner, C.; Stokes, E.K.; Dreinhofer, K.; Monsbakken, J.; Clarke, S.; ... more authors ( Medical Journals Sweden AB , 2020 , Article)
      COVID-19 has become a pandemic with strong influence on health systems. In many cases it leads to a disruption of rehabilitation service provision. On the other hand, rehabilitation must be an integral part of COVID-19 ...

    • Willingness to participate in genome testing: a survey of public attitudes from Qatar 

      Abdul-Rahim, Hanan; Ismail, Said; Hasan, Amel; Fadl, Tasnim; Khaled, Salma; ... more authors ( Springer , 2020 , Article)
      Genomics has the potential to revolutionize medical approaches to disease prevention, diagnosis, and treatment, but it does not come without challenges. The success of a national population-based genome program, like the ...

    • Women's Health and Well-Being in the United Nations Sustainable Development Goals: A Narrative Review of Achievements and Gaps in the Gulf States. 

      Daher-Nashif, Suhad; Bawadi, Hiba ( MDPI , 2020 , Article)
      In 2014, United Nations member states proposed a set of sustainable development goals (SDGs) to help further the millennium development goals that they had proposed in New York in 2000. Of these 13 SDGs, Goal 3 (i.e., SDG ...

    • Women-Focused Cardiac Rehabilitation Delivery Around the World and Program Enablers to Support Broader Implementation 

      Gabriela Lima de Melo, Ghisi; Supervia, Marta; Turk-Adawi, Karam; Beleigoli, Alline; Contractor, Aashish; ... more authors ( Elsevier , 2024 , Article)
      BackgroundWomen are less likely than men to use cardiac rehabilitation (CR); thus, women-focused (W-F) CR was developed. Implementation of W-F CR globally was investigated, as well as barriers and enablers to its delivery. ...

    • Women-Only Cardiac Rehabilitation Delivery Around the World 

      Turk-Adawi, Karam; Supervia, Marta; Lopez-Jimenez, Francisco; Adawi, Anfal; Sadeghi, Masoumeh; ... more authors ( Elsevier , 2020 , Article  &   Conference Proceedings)
      Background: Women utilize cardiac rehabilitation (CR) significantly less than men. Gender-tailored CR improves adherence and mental health outcomes when compared to traditional programs. This study ascertained the ...

    • WORKSITE HEALTH PROMOTION SCORE: TO ASSESS A HEALTH PROMOTIONAL WORKER SETTING 

      Gamage, Anuji; Seneviratne, Rohini; Hanna, Fahad ( Wolters Kluwer Health , 2016 , Conference Paper)
      Objective: Workplace play a central role in the lives of employees and their potential as health-promotional-setting is enormous as it could aim at keeping employees healthy which is considered a key long-term human asset ...

    • Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants 

      Bin, Zhou; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; ... more authors ( Elsevier , 2017 , Article)
      BackgroundRaised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, ...

    • Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants 

      Bin, Zhou; Carrillo-Larco, Rodrigo M; Danaei, Goodarz; Riley, Leanne M; Paciorek, Christopher J; ... more authors (2021 , Article)
      Background Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, ...

    • A YEAST TWO-HYBRID SCREEN REVEALS A STRONG INTERACTION BETWEEN THE LEGIONELLA CHAPERONIN Hsp60 AND THE HOST CELL SMALL HEAT SHOCK PROTEIN Hsp10 

      Nasrallah, Gheyath K. ( Akadémiai Kiadó , 2015 , Article)
      L. pneumophila is an intracellular bacterium that replicates inside a membrane- bound vacuole called Legionella-containing vacuole (LCV), where it plentifully liberates its HtpB chaperonin. From LCV, HtpB reaches the ...

    • Zebrafish (Danio rerio) as a Model for the Study of Developmental and Cardiovascular Toxicity of Electronic Cigarettes 

      Hussen, Eman; Aakel, Nada; Shaito, Abdullah A.; Al-Asmakh, Maha; Abou-Saleh, Haissam; ... more authors ( MDPI , 2023 , Article Review)
      The increasing popularity of electronic cigarettes (e-cigarettes) as an alternative to conventional tobacco products has raised concerns regarding their potential adverse effects. The cardiovascular system undergoes intricate ...

    • Zebrafish as a Model for Anticancer Nanomedicine Studies. 

      Al-Thani, Hissa F; Shurbaji, Samar; Yalcin, Huseyin C ( MDPI , 2021 , Article Review)
      Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ...

    • Zebrafish larvae as a model to demonstrate secondary iron overload. 

      Nasrallah, Gheyath K; Younes, Nadin N; Baji, Missbah H; Shraim, Amjad M; Mustafa, Ibrahim ( Wiley , 2018 , Article)
      Thalassemia is the most common genetically inherited blood disorder arising from a defect in hemoglobin production, resulting in ineffective erythropoiesis and severe hemolytic anemia. While transfusion therapy corrects ...

    • Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros 

      Mesmar, J.; Mesmar, Joelle; Fardoun, Manal M.; Abdallah, Rola; Al Dhaheri, Yusra; ... more authors ( MDPI AG , 2021 , Article)
      Pancreatic cancer (PC) is the fourth leading cause of all cancer-related deaths. Despite major improvements in treating PC, low survival rate remains a major challenge, indicating the need for alternative approaches, ...

    • Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells 

      Fardoun, Manal; Al-Shehabi, Tuqa; El-Yazbi, Ahmed; Issa, Khodr; Zouein, Fouad; ... more authors ( Hindawi Limited , 2017 , Article)
      Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. Atherosclerosis is a CVD characterized by plaque formation resulting from inflammation-induced insults to endothelial cells, monocytes, and ...