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Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy
(
Elsevier
, 2017 , Article)
Abstract We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell-penetrating peptide, the short ...
Bioavailability and hypolipidemic effects of peanut skin polyphenols
(
Mary Ann Liebert, Inc.
, 2015 , Article)
Peanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly
consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type ...
Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar.
(
Elsevier
, 2018 , Article)
Clinical Exome Sequencing (CES) has increasingly become a popular diagnostic tool in patients suffering from genetic disorders that are clinically and genetically complicated. Myeloproliferative Neoplasms (MPNs) is an ...
Screening and brief interventions for adolescent alcohol use disorders presenting through emergency departments: a research programme including two RCTs
(
NIHR Journals Library
, 2020 , Article)
BACKGROUND:
Alcohol consumption and related harm increase steeply from the ages of 12–20 years. Adolescents in the UK are among the heaviest drinkers in Europe. Excessive drinking in adolescents is associated with ...
Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos
(
Elsevier
, 2020 , Article)
Surfactants are widely used in the industry of detergents, household products, and cosmetics. SAPDMA is a cationic surfactant that is used mostly in cosmetics, conditioning agents and has recently gained attention as a ...
Resting Energy Expenditure in a Controlled Group of Young Arab Females: Correlations with Body Composition and Agreement with Prediction Equations
(
Scientific Research Publishing
, 2013 , Article)
Objectives: To assess correlates of body compositions measures and resting energy expenditure (REE) in young Arab females, and to compare measured REE values with values calculated from REE predictive equations. Methods: ...
Potential Nutrigenomic Approaches to Reduce the High Incidence of Obesity in Qatar
(
OMICS International
, 2016 , Article)
Obesity prevalence has been growing exponentially over the last few decades, with a high impact in high-income countries, like Qatar. Several approaches are attempting to understand the causes of this phenomenon however ...
Glycemic index of selected carbohydrate-based foods consumed in Qatar
(
Taylor & Francis
, 2010 , Article)
This study determined the glycemic index (GI) of selected carbohydrate-rich foods consumed in
Qatar. Recruited volunteers (n = 19) consumed two reference foods, glucose and white bread,
and 10 test foods. The foods tested ...
Dietary Pattern, Hypertension and Cognitive Function in an Older Population: 10-Year Longitudinal Survey.
(
Frontiers Media
, 2018 , Article)
There is a paucity of studies that have explored the association between dietary pattern and cognitive function, and whether there is an interaction between dietary pattern and hypertension in relation to older people's ...
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...