Browsing Biomedical Research Center by Subject "Diabetes"
Now showing items 1-7 of 7
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Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
( Elsevier , 2021 , Article)Drug delivery systems or vectors are usually needed to improve the bioavailability and effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an organ, tissue or cellular level. However, emerging ... -
EndMT regulation by small RNAs in diabetes-associated fibrotic conditions: potential link with oxidative stress
( Frontiers Media , 2021 , Article)Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ dysfunction, disability, and increased mortality. ... -
Impact of physical exercise on gut microbiome, inflammation, and the pathobiology of metabolic disorders
( Society for Biomedical Diabetes Research , 2019 , Article)BACKGROUND: The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and ... -
In vivo Analysis of Clausena anisata (Willd.) Hook. f. ex Benth Crude and SNP Extracts Against Antioxidant and Hypoglycemic Activity
( DYR Labs Pvt. Ltd. , 2018 , Article)Type II diabetes mellitus which is a chronic metabolic disorder is characterized by insulin resistance. Due to the serious side effects of synthetic antidiabetic drugs, the search for safer and more efficacious hypoglycemic ... -
Influenza Prevalence and Vaccine Efficacy in Diabetic Patients in Qatar
( Qatar University Press , 2021 , Poster)Introduction: Diabetes (DM) is often recognized as ?an independent risk factor for developing severe respiratory tract infections. Influenza infections are associated with higher hospitalization, morbidity and mortality ... -
Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus.
( Hindawi Publishing Corporation , 2017 , Article)The incidence of diabetes mellitus is rapidly increasing throughout the world. Although the exact cause of the disease is not fully clear, perhaps, genetics, ethnic origin, obesity, age, and lifestyle are considered as few ... -
Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors
( Springer , 2023 , Article Review)Sodium-glucose co-transporter 2 (SGLT2) inhibitors represent one type of new-generation type 2 diabetes (T2DM) drug treatment. The mechanism of action of an SGLT2 inhibitor (SGLT2i) in treating T2DM depends on lowering ...