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Biomechanical Investigation of Disturbed Hemodynamics-Induced Tissue Degeneration in Abdominal Aortic Aneurysms Using Computational and Experimental Techniques.
(
Frontiers Media
, 2019 , Article Review)
Abdominal aortic aneurysm (AAA) is the dilatation of the aorta beyond 50% of the normal vessel diameter. It is reported that 4-8% of men and 0.5-1% of women above 50 years of age bear an AAA and it accounts for ~15,000 ...
Fluid Flow Characteristics of Healthy and Calcified Aortic Valves Using Three-Dimensional Lagrangian Coherent Structures Analysis
(
MDPI
, 2021 , Article)
Aortic valve calcification is an important cardiovascular disorder that deteriorates the accurate functioning of the valve leaflets. The increasing stiffness due to the calcification prevents the complete closure of the ...
Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages
(
Frontiers Media
, 2021 , Article)
Flow-driven hemodynamic forces on the cardiac tissues have critical importance, and have a significant role in the proper development of the heart. These mechanobiological mechanisms govern the cellular responses for the ...
Blood Flow Disturbance and Morphological Alterations Following the Right Atrial Ligation in the Chick Embryo.
(
Frontiers Media
, 2022 , Article)
Collectively known as congenital heart defects (CHDs), cardiac abnormalities at birth are the most common forms of neonatal defects. Being principally responsible for the heart's pumping power, ventricles are particularly ...
Computational Analysis of Wall Shear Stress Patterns on Calcified and Bicuspid Aortic Valves : Focus on Radial and Coaptation Patterns
(
MDPI
, 2021 , Article)
Calcification and bicuspid valve formation are important aortic valve disorders that disturb the hemodynamics and the valve function. The detailed analysis of aortic valve hemodynamics would lead to a better understanding ...