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Author El Banhawy, M. A [محمود احمد البنهاوي]en_US
Author Anwar, Ibrahim M.en_US
Available date 2009-11-25T15:13:22Zen_US
Publication Date 1984en_US
Publication Name Qatar University Science Bulletin
Citation Qatar University Science Bulletin, 1984, Vol. 4, Pages 117-124.en_US
URI http://hdl.handle.net/10576/9690en_US
Abstract Normal mice exposed to X-rays showed distinct external symptoms and died mostly on the 13th or 14th day after irradiation. Pathological symptoms were more exaggerated in mice diseased with hepatoma and subjected to the effects of irradiation. These animals did not survive beyond the 4th day following treatment. Histologically, the normal liver displays the characteristic pattern of lobulation and disposition of hepatic cells. The whole tissue is enveloped by a layer of squamous epithelium. The liver of X-ray irradiated mice shows cloudy swelling in its cells, which became lightly stained and the nuclei display distinct signs of karyolysis. Hepatic blood vessels are markedly enlarged, engorged with blood and their limiting membranes and deteriorated. Hepatoma has lost completely the characteristic pattern of the healthy liver. Cells are much smaller in size, being oval or spindle shaped and irregularly disposed with their nuclei obviously injured. Hepatoma treated with X-rays show prominent signs of deterioration. Most of the tissue has been occupied by prominent vacuoles of variable sizes. The inter-vacuolar tissue is formed of necrotic cells.en_US
Language enen_US
Publisher Qatar Universityen_US
Subject Zoologyen_US
Subject علم الحيوانar
Title Comparative Histopathological Studies On The Effects Of Ionizing X-Ray Irradiation On Normal Liver And Hepatomaen_US
Alternative Title دراسة مقارنة لتأثير الأشعة السينية على الخلايا الكبدية السامة والسرطانيةar
Type Articleen_US
Pagination 117-124en_US
Volume Number 4en_US
Alternative Abstract اتضح من البحث الحالي ان الخلايات الكبدية السرطانية تختلف اختلافا بينيا في شكلها وتركيبها عن خلايا الكبد السليمة . فهي في الحالة الأولى مرتبة بطريقة مميزة على هيئة فصيصات صغيرة يتوسط كل منها وعاء دموي تبطنه خلايا طلائية حرشفية ، ولا يشاهد شيء هذا الوعاء . فاذا تحول هذا الكبد الى الحالة السرطانية اختل هذا النظام وفقدت الخلايا نظامها وشكلها المميز واصبحت صغيرة الحجم جدا وتأخذ شكلا مغزليا غير مألوف في الحالات العادية . وعند التعرض للأشعة السينية تتأثر كل من الكبد والخلايا السرطانية تأثرا بالغا ينعكس في شكل الخلايا وحجمها الأوعية الدموية الموجودة بها .


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