Browsing by Author "Eid, Ali H."
Now showing items 1-20 of 42
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2-Nucleobase-substituted 4,6-Diaminotriazine Analogs: Synthesis and Anti-cancer Activity in 5-Fluorouracil-Sensitive and Resistant Colorectal Cancer Cells.
Hamze, Khalil; Abdallah, Rola H; Younis, Nour K; Fardoun, Manal; Darwiche, Nadine; Kobeissy, Firas; Iratni, Rabah; Bouhadir, Kamal; Eid, Ali H... more authors ... less authors ( Bentham Science Publishers , 2022 , Article)Cancer continues to be the second leading cause of death worldwide with colorectal cancer (CRC) being the third most common type. Despite significant advances in cancer therapies, current treatment of CRC remains suboptimal. ... -
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
Al-Shehabi, Tuqa Saleh; Iratni, Rabah; Eid, Ali H. ( Elsevier , 2016 , Article)Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ... -
Anti-hypertensive Herbs and their Mechanisms of Action: Part I
Al Disi, Sara S.; Anwar, M. Akhtar; Eid, Ali H. ( Frontiers Media , 2016 , Article)The use of herbal therapies for treatment and management of cardiovascular diseases (CVDs) is increasing. Plants contain a bounty of phytochemicals that have proven to be protective by reducing the risk of various ailments ... -
Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II
Anwar, M. Akhtar; Al Disi, Sara S.; Eid, Ali H. ( Frontiers Media , 2016 , Article)Traditional medicine has a history extending back to thousands of years, and during the intervening time, man has identified the healing properties of a very broad range of plants. Globally, the use of herbal therapies to ... -
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Munusamy, Shankar; Gopalakrishnan, Akila; Ravindran, Sreenithya; Alali, Feras; Eid, Ali H. ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates ... -
Antihypertensive indigenous lebanese plants: Ethnopharmacology and a clinical trial
Samaha, Ali A.; Fawaz, Mirna; Salami, Ali; Baydoun, Safaa; Eid, Ali H. ( MDPI AG , 2019 , Article)Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Swapna, Thomas; Ouhtit, Allal; Al Khatib, Hebah A.; Eid, Ali H.; Mathew, Shilu; Nasrallah, Gheyath K.; Emara, Mohamed M.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
Cadmium induces migration of colon cancer cells: Roles of reactive oxygen species, p38 and cyclooxygenase-2
Naji, Sara; Issa, Khodr; Eid, Assaad; Iratni, Rabah; Eid, Ali H. ( Cell Physiol Biochem Press GmbH & Co KG , 2019 , Article)Background/Aims: Cadmium (Cd) is a heavy metal contaminant whose toxicity is associated with colorectal cancer (CRC). However, the underlying molecular mechanisms of Cd-induced CRC malignancy remain obscure. Methods: A ... -
Chemical Analysis and Investigation of Biological Effects of Salvia officinalis Essential Oils at Three Phenological Stages
Assaggaf, Hamza M.; Naceiri Mrabti, Hanae; Rajab, Bodour S.; Attar, Ammar A.; Alyamani, Reema A.; Hamed, Munerah; El Omari, Nasreddine; El Menyiy, Naoual; Hazzoumi, Zakaria; Benali, Taoufiq; Al-Mijalli, Samiah Hamad; Zengin, Gokhan; AlDhaheri, Yusra; Eid, Ali H.; Bouyahya, Abdelhakim... more authors ... less authors ( MDPI , 2022 , Article)Salvia officinalis is a medicinal plant used to treat some diseases, including microbial infections and diabetes. Different studies showed the biological and pharmacological properties of this species. The aim of this study ... -
Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene
Anwar, M. Akhtar; Kheir, Wassim Abou; Eid, Stephanie; Fares, Joanna; Liu, Xiaoqi; Eid, Ali H.; Eid, Assaad A.... more authors ... less authors ( Ivyspring International Publisher , 2014 , Article)Both diabetes and cancer are prevalent diseases whose incidence rates are increasing worldwide, especially in countries that are undergoing rapid industrialization changes. Apparently, lifestyle risk factors including diet, ... -
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase
Cecchi, Marta; Mannini, Antonella; Lapucci, Andrea; Silvano, Angela; Lulli, Matteo; Luceri, Cristina; D’Ambrosio, Mario; Chiarugi, Alberto; Eid, Ali H.; Parenti, Astrid... more authors ... less authors ( Frontiers Media , 2022 , Article)In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement ... -
Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival.
Posadino, Anna Maria; Giordo, Roberta; Cossu, Annalisa; Nasrallah, Gheyath K; Shaito, Abdullah; Abou-Saleh, Haissam; Eid, Ali H; Pintus, Gianfranco... more authors ... less authors ( MDPI , 2019 , Article)Dietary intake of natural antioxidants is thought to impart protection against oxidative-associated cardiovascular diseases. Despite many in vivo studies and clinical trials, this issue has not been conclusively resolved. ... -
Flavonoids in hypertension: a brief review of the underlying mechanisms.
Maaliki, Dina; Shaito, Abdullah A; Pintus, Gianfranco; El-Yazbi, Ahmed; Eid, Ali H ( Elsevier , 2019 , Article)Flavonoids are a diverse group of bioactive polyphenolic compounds abundant in dietary plants and herbs. Regular consumption of flavonoids exerts cardio-vasculoprotective effects and may reduce the onset or progression of ... -
Garlic for cardiovascular disease: Prevention or treatment?
Alali, Feras Q.; El-Elimat, Tamam; Khalid, Lila; Hudaib, Reema; Al-Shehabi, Tuqa Saleh; Eid, Ali H.... more authors ... less authors ( Bentham Science Publishers B.V. , 2017 , Article Review)Cardiovascular disease (CVD) is the leading cause of global mortality with a substantial economic impact. The annual deaths are expected to increase in the next decade. An array of dietary supplements is being used by ... -
Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events
Anwar, M. Akhtar; Saleh, Alaaeldin I.; Al Olabi, Reem; Al Shehabi, Tuqa S.; Eid, Ali H. ( Elsevier Inc. , 2016 , Article Review)Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden. Accumulating epidemiological and experimental evidence suggest that adult-onset hypertension may have its origins during ... -
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
Shaito, Abdullah; Thuan, Duong Thi Bich; Phu, Hoa Thi; Nguyen, Thi Hieu Dung; Hasan, Hiba; Halabi, Sarah; Abdelhady, Samar; Nasrallah, Gheyath K.; Eid, Ali H.; Pintus, Gianfranco... more authors ... less authors ( Frontiers Media S.A. , 2020 , Article)Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing prevalence. They remain the leading causes of morbidity and mortality worldwide. The use of medicinal herbs continues to be an ... -
Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview
Dania, Kattan; Barsa, Chloe; Mekhijian, Sarin; Shakkour, Zaynab; Jammoul, Maya; Doumit, Mark; Zabala, Maria Camila Pareja; Darwiche, Nadine; Eid, Ali H.; Mechref, Yehia; Wang, Kevin K.; de Rivero Vaccari, Juan Pablo; Munoz Pareja, Jennifer C.; Kobeissy, Firas... more authors ... less authors ( Elsevier , 2023 , Article)Given the ambiguity surrounding traumatic brain injury (TBI) pathophysiology and the lack of any Food and Drug Administration (FDA)-approved neurotherapeutic drugs, there is an increasing need to better understand the ... -
Inflammogenesis of Secondary Spinal Cord Injury
Anwar, M. Akhtar; Al Shehabi, Tuqa S.; Eid, Ali H. ( Frontiers Media , 2016 , Article)Spinal cord injury (SCI) and spinal infarction lead to neurological complications and eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major contributors to morbidity. Our understanding ... -
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
Eid, Ali H; El-Yazbi, Ahmed F; Zouein, Fouad; Arredouani, Abdelilah; Ouhtit, Allal; Rahman, Md M; Zayed, Hatem; Pintus, Gianfranco; Abou-Saleh, Haissam... more authors ... less authors ( Frontiers Media , 2018 , Article Review)Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ... -
Lipid-lowering therapies for atherosclerosis: Statins, fibrates, ezetimibe and pcsk9 monoclonal antibodies
Ali, A.H.; Younis, Nour; Abdallah, Rola; Shaer, Farah; Dakroub, Ali; Ayoub, Mohammed Akli; Iratni, Rabah; Yassine, Hadi Mohamad; Zibara, Kazem; Orekhov, Alexander; El-Yazbi, Ahmed Fawzy; Eid, Ali H.... more authors ... less authors ( Bentham Science Publishers , 2021 , Article Review)Cardiovascular disease (CVD) remains the primary cause of global morbidity and mortality. CVD includes various life-threatening conditions such as myocardial infarction, stroke and peripheral arterial diseases. In this ...